Results 91 to 100 of about 3,892 (211)

Dose-response study of N,N-dimethyltryptamine in humans. I. Neuroendocrine, autonomic, and cardiovascular effects

open access: yes, 1994
BACKGROUND: To begin applying basic neuropharmacological hypotheses of hallucinogenic drug actions to humans, we generated dose-response data for intravenously administered dimethyltryptamine fumarate\u27s (DMT) neuroendocrine, cardiovascular, autonomic,
Qualls, Clifford R, Strassman, Rick J
core  

Chronic intermittent exposure to ayahuasca during aging does not affect memory in mice

open access: yesBrazilian Journal of Medical and Biological Research
The Quechua term ayahuasca refers to a beverage obtained from decoctions of the liana Banisteriopsis caapi with leaves of Psychotria viridis. The ritualistic use of ayahuasca is becoming a global phenomenon, with some individuals using this beverage ...
N.F. Correa-Netto   +7 more
doaj   +1 more source

Determination and analysis of N,N-dimethyltryptamine in plant and biological matrices

open access: yes, 2023
Tato práce se zabýva N,N-dimethyltryptaminem, což je velmi silné endogenní serotonergní psychedelikum. První část je věnována teoretickým poznatkům, jako je historie, výskyt, chemické, fyzikální a farmakologické vlastnosti.
Hejnochová, Kristýna
core   +1 more source

Therapeutic properties of ayahuasca component N,N-Dimethyltryptamine in a pre-clinical model of Parkinson's disease

open access: yes
Parkinson's disease is a progressive neurodegenerative disorder with increasing global prevalence, primarily driven by population ageing. A hallmark of the disease is the degeneration of nigrostriatal dopaminergic neurons, accompanied by marked ...
Giné Domínguez, Elena   +8 more
core   +1 more source

Parapsychology, N, N-Dimethyltryptamine and the Pineal Gland

open access: yes, 2019
In the last decades, one of the psychedelic substances which has gained high attention for its implications in several para-psychological phenomena (including out-of-body states, deep changes in sensory perception, mood, and thought, travels in ...
Bragazzi, Nicola Luigi   +8 more
core  

Safety and tolerability profile of N,N-Dimethyltryptamine: a systematic review of clinical trials

open access: yes
N,N-Dimethyltryptamine (DMT) is presently emerging as a candidate in clinical trials aimed at addressing treatment-resistant depression. This condition is characterized by its chronic and incapacitating nature, featuring heightened severity and prolonged
Wiesław Jerzy Cubała   +2 more
core   +1 more source

Conformational, spectroscopic and nonlinear optical properties of biologically active N,N-dimethyltryptamine molecule: A theoretical study

open access: yes, 2014
The effective psychoactive properties of N,N-dimethyltryptamine (DMT) known as the near-death molecule have encouraged the imagination of many research disciplines for several decades. Although there is no theoretical study, a number of paper composed by
Atalay Y.   +7 more
core   +1 more source

Best practices for first psychedelic experiences: harm reduction advice from the psychedelic community

open access: yesHarm Reduction Journal
Background The use of psychedelics is currently increasing in the United States. Awareness of clinical trials investigating the therapeutic applications of psychedelics may result in a record number of people who use psychedelics for the first-time. This
Daniel J. Kruger   +7 more
doaj   +1 more source

An ontogenic study of the behavioral effects of chronic intermittent exposure to ayahuasca in mice

open access: yesBrazilian Journal of Medical and Biological Research
Ayahuasca is a beverage obtained from decoctions of the Banisteriopsis caapi plus Psychotria viridis. In religious contexts, ayahuasca is used by different age groups.
N.F. Correa-Netto   +8 more
doaj   +1 more source

Continuous flow synthesis of N,N-dimethyltryptamine (DMT) analogues with therapeutic potential

open access: yes
Herein, we describe the continuous flow synthesis and in-line extraction of N,N-dimethyltryptamine (DMT) and several of its analogues using a Fischer indole reaction, along with a larger gram scale synthesis (4.75 g) of the model compound. These products
Stevens, Christian   +4 more
core   +1 more source

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