Results 131 to 140 of about 606 (153)
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Biosynthetic origin of C-37 and C-38 in the polyether toxins okadaic acid and dinophysistoxin-1

Journal of the Chemical Society, Chemical Communications, 1994
Stable isotope incorporation experiments have shown that carbons 37 and 38 in okadaic acid and dinophysistoxin-1 are derived from glycolate.
Judy Needham   +3 more
openaire   +1 more source

Effects of microorganisms, temperature and irradiation on the stability of dissolved okadaic acid and dinophysistoxin-1 in seawater

Marine Environmental Research
Diarrhetic shellfish toxins (DSTs) are widespread in marine environments, posing potential threats to marine ecosystems, shellfish aquaculture, and human health. Despite their prevalence, knowledge of the stability of dissolved DSTs in seawater is still limited.
Jiangbing Qiu   +5 more
openaire   +2 more sources

Inhibition Equivalency Factors for Dinophysistoxin-1 and Dinophysistoxin-2 in Protein Phosphatase Assays: Applicability to the Analysis of Shellfish Samples and Comparison with LC-MS/MS

Journal of Agricultural and Food Chemistry, 2013
The protein phosphatase inhibition assay (PPIA) is a well-known strategy for the determination of diarrheic shellfish poisoning (DSP) lipophilic toxins, which deserves better characterization and understanding to be used as a routine screening tool in monitoring programs. In this work, the applicability of two PPIAs to the determination of okadaic acid
Mònica Campàs   +2 more
exaly   +3 more sources

Beware of phycotoxin (okadaic acid and dinophysistoxin-1) accumulation in early post-restoration period

Water Research
Human-induced environmental pollution and ecological degradation are worsening, prompting remediation efforts to reverse the situation. However, it remains unclear whether these interventions will create new ecological risks or contaminate the water environment.
Qi Qiao   +8 more
openaire   +2 more sources

Kinetics of diarrhetic shellfish poisoning toxins, okadaic acid, dinophysistoxin-1, pectenotoxin-6 and yessotoxin in scallops Patinopecten yessoensis

Fisheries Science, 2005
Four toxins, okadaic acid (OA), dinophysistoxin-1 (DTX1), pectenotoxin-6 (PTX6), and yessotoxin (YTX), all associated with diarrhetic shellfish poisoning (DSP), were administered via syringe to Scallops Patinopecten yessoensis and their distribution in the hepatopancreas, adductor muscle, and combined other tissues (mantle, gill, gonad) was analyzed by
Toshiyuki SUZUKI   +6 more
openaire   +3 more sources

Okadaic acid and dinophysistoxin-1, non-TPA-type tumor promoters, stimulate prostaglandin E2 production in rat peritoneal macrophages

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1989
Okadaic acid and dinophysistoxin-1 isolated from a black sponge, Halichondria okadai are non-12-O-tetrade-canoylphorbol 13-acetate (non-TPA)-type tumor promoters of mouse skin. Okadaic acid at concentrations of 10-100 ng/ml stimulated prostaglandin E2 production in rat peritoneal macrophages.
K, Ohuchi   +6 more
openaire   +2 more sources

Combined effects of polystyrene nanoplastics and dinophysistoxin-1 (DTX1) on physiological performance of marine diatom Thalassiosira minima

Water Research
Currently micro- and nanoplastics (MNPs) and microalgal toxins have become two typical groups of emerging contaminants in various coastal regions worldwide. However, the knowledge about their combined effects on marine organisms is still limited. This study explored the single and combined effects of polystyrene nanoplastics (PSNPs) at 50 mg L-1 and ...
Natnael Sisay Demo   +5 more
openaire   +2 more sources

High-performance liquid chromatographic resolution of dinophysistoxin-1 and free fatty acids as 9-anthrylmethyl esters

Journal of Chromatography A, 1994
Abstract Resolution of a mixture of dinophysistoxin-1 (DTX1) and free fatty acids (FFAS) including eleven components which are the dominant FFAs in mussels and scallops was carried out by high-performance liquid chromatography (HPLC) with fluorimetric detection after their derivatization with 9-anthryldiazomethane (ADAM).
openaire   +1 more source

Histopathological studies on experimental marine toxin poisoning. I. Ultrastructural changes in the small intestine and liver of suckling mice induced by dinophysistoxin-1 and pectenotoxin-1

Toxicon, 1986
Sequential ultrastructural changes were studied in mouse digestive organs after i.p. injections of dinophysistoxin-1 and pectenotoxin-1, causative agents of diarrhetic shellfish poisoning. Dinophysistoxin-1, a diarrheagenic substance, produced severe mucosal injuries in the small intestine within 1 hr after the administration of the toxin. The injuries
K, Terao, E, Ito, T, Yanagi, T, Yasumoto
openaire   +2 more sources

Toxicity of the diarrhetic marine phycotoxins okadaic acid and its analogues dinophysistoxin-1 and-2 in the human hepatic heparg cell line

2014
Presented at the 10th International Meeting of the International-Society-for-the-Study-of-Xenobiotics (ISSX) in Toronto (Canada), Sept 29 - Oct 03, 2013 ; International ...
Ferron, Pierre-Jean   +5 more
openaire   +1 more source

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