Results 81 to 90 of about 196 (117)
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Structural analysis and inhibition capacity of dioscorin protein yam: Theoretical study by molecular docking and dynamic simulations

Archives of Insect Biochemistry and Physiology, 2023
AbstractProteases such as trypsins in the gut of Spodoptera frugiperda are responsible for breaking down dietary proteins into amino acids necessary for insect growth and development. In this study, we characterized the insecticidal potential of dioscorin, the storage protein of yam (Dioscorea alata), using molecular docking and molecular dynamics ...
José Severiche‐Castro   +4 more
openaire   +2 more sources

Effects of pH on the total phenolic compound, antioxidative ability and the stability of dioscorin of various yam cultivars

Food Chemistry, 2008
Abstract The purposes of this study were to investigate the antioxidative activity and the stability of dioscorin of various yam cultivars (Mingchien (MC), Tainung No. 2 (TN2) and Keelung (KL)) under the influences of varying pH. Total phenolic contents from all yam varieties were the highest at pH 5, but gradually decreased with elevated pH.
Kuo-Wei Lin
exaly   +2 more sources

In vitro α-Amylase and α-Glucosidase Inhibitory Activity of Dioscorin from Dioscorea alata

Applied Science and Engineering Progress, 2023
Dioscorea alata is a species of yam found in many countries in Southeast Asia. It contains many bioactive compounds consisting of steroidal saponins, phenolic compounds flavonoids, polysaccharides, and proteins. Eighty to eighty-five of the soluble proteins in the tuber of D. alata are dioscorin.
Anocha Sansud   +3 more
openaire   +1 more source

Antioxidant and trypsin inhibition activity of dioscorin influenced by yam cultivars and eluent pH

International Journal of Food Science and Technology, 2012
SummaryThe total antioxidant activity (TAA) and trypsin inhibition activity (TIA) of storage protein dioscorin from six yam cultivars (Dashan, Hualien No. 3, Keelung, Mingchien, Tainong No. 2, and Japanese yam) were demonstrated. Japanese yam had the highest TAA and the lowest calculated EC50 at any purification stage.
Chen-Tien Chang, Kuo-Wei Lin
exaly   +2 more sources

Suppression of Allergic Reactions in Ovalbumin-Sensitized Mice by Yam Storage Proteins Dioscorins

Journal of Agricultural and Food Chemistry, 2013
To study the biomedical functions of dioscorins isolated from various species of Dioscorea , we investigated their antiallergic potential using an OVA-induced allergy mouse model. All the dioscorins suppressed allergic reactions by decreasing the serum IgE and histamine levels.
Yu-Jhen, Hsu   +3 more
openaire   +2 more sources

Effects of heating temperature on the total phenolic compound, antioxidative ability and the stability of dioscorin of various yam cultivars

Food Chemistry, 2007
Abstract The purposes of this study were to investigate the effects of different heating temperatures on the antioxidative activity of yams and on the stability of dioscorin of various yam cultivars (Mingchien, Tainung No. 2 and Keelung). Results from crude yam extracts of all varieties showed decreases in total phenolic and dioscorin contents, DPPH ...
Kuo-Wei Lin
exaly   +2 more sources

Class A dioscorins of various yam species suppress ovalbumin-induced allergic reactions

Immunopharmacology and Immunotoxicology, 2014
Dioscorins, the primary storage proteins in yam tubers, of different species exhibited varying immunomodulatory activities in mice. We inferred that this might be attributed to the various isoforms in the yam tubers.We aimed to investigate the antiallergic potential of the Class A dioscorins of various yam species using the ovalbumin (OVA)-induced ...
Ching-Chi, Yang, Kuo-Chih, Lin
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Antioxidant Activities of Dioscorin, the Storage Protein of Yam (Dioscorea batatas Decne) Tuber

Journal of Agricultural and Food Chemistry, 2001
Dioscorin, the storage protein of yam (Dioscorea batatas Decne) tuber (which is different from dioscorine found in tubers of Dioscorea hirsuta), was purified to homogeneity after DE-52 ion exchange column according to the methods of Hou et al. (J. Agric. Food Chem. 1999, 47, 2168-2172). A single band of 32 kDa dioscorin was obtained on a sodium dodecyl
W C, Hou   +6 more
openaire   +2 more sources

Modulation of the Nicotinic Acetylcholine Receptor by Dioscorine in Clonal Rat Phaeochlomocytoma (PC12) Cells

Pesticide Biochemistry and Physiology, 1999
Abstract Dioscorine is a toxin isolated from the tubers of tropical yam, Dioscorea hispida Schlussel that has insecticidal and antifeedant activities. The effects of dioscorine on the neuronal nicotinic acetylcholine receptor in rat clonal phaeochlomocytoma (PC12) cells were studied using whole-cell and single-channel patch clamp techniques ...
Keiichi Nagata   +4 more
openaire   +1 more source

The incorporation of 3-hydroxy-3-methylglutaric acid into the lactone ring of dioscorine in Dioscorea hispida

Phytochemistry, 1989
Abstract [3- 14 C]- and [3,3′- 13 C 2 ,3- 14 C]-3-Hydroxy-3-methylglutaric acid were administered to Dioscorea hispida plants, resulting in the formation of labelled dioscorine (0.2% absolute incorporation). A chemical degradation indicated that there was a non-random incorporation of 14 C into the lactone ring of the alkaloid, the major part of ...
Edward Leete, Robert H. Michelson
openaire   +1 more source

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