Results 141 to 150 of about 1,995 (163)
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Biosynthesis of diosgenin from 26-hydroxycholesterol in dioscorea floribunda
Phytochemistry, 1970Abstract 26-Hydroxycholesterol-26- 14 C was converted by a Dioscorea floribunda plant to diosgenin. This result suggests that oxygenation at C-26 may be the first step in the biosynthesis of diosgenin from cholesterol. No diosgenin was formed from kryptogenin-26- 14 C by D.
Raymond D. Bennett +2 more
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Genes & Genomics, 2017
Dioscorea zingiberensis is the main plant source of diosgenin, a precursor for the production of steroid hormones used in the pharmaceutical industry. The extraction process of diosgenin from D. zingiberensis can generate high-acid and high-strength wastewater on a large scale and can threaten the environment.
Wenping Hua +6 more
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Dioscorea zingiberensis is the main plant source of diosgenin, a precursor for the production of steroid hormones used in the pharmaceutical industry. The extraction process of diosgenin from D. zingiberensis can generate high-acid and high-strength wastewater on a large scale and can threaten the environment.
Wenping Hua +6 more
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Metabolic Engineering, 2023
Cholesterol serves as a key precursor for many high-value chemicals such as plant-derived steroidal saponins and steroidal alkaloids, but a plant chassis for effective biosynthesis of high levels of cholesterol has not been established. Plant chassis have significant advantages over microbial chassis in terms of membrane protein expression, precursor ...
Xue Yin +8 more
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Cholesterol serves as a key precursor for many high-value chemicals such as plant-derived steroidal saponins and steroidal alkaloids, but a plant chassis for effective biosynthesis of high levels of cholesterol has not been established. Plant chassis have significant advantages over microbial chassis in terms of membrane protein expression, precursor ...
Xue Yin +8 more
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Industrial Crops and Products, 2020
Abstract Induction of hairy roots stemmed from Agrobacterium rhizogenes transformation, is a key step to reach mass production of secondary metabolites in medicinal plants. Accordingly, this study is aimed to investigate potential impact of different A.
Farnaz Zolfaghari +4 more
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Abstract Induction of hairy roots stemmed from Agrobacterium rhizogenes transformation, is a key step to reach mass production of secondary metabolites in medicinal plants. Accordingly, this study is aimed to investigate potential impact of different A.
Farnaz Zolfaghari +4 more
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Gene
Next-generation sequencing (NGS) has revolutionized the analysis of specific genes, pathways, and their regulation in various species. Tribulus terrestris L., an annual medicinal herb of Zygophyllaceae family, has gained significant attention due to its diverse medicinal properties, including anti-inflammatory, antimicrobial, and anti-cancer effects ...
Parul Tyagi +3 more
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Next-generation sequencing (NGS) has revolutionized the analysis of specific genes, pathways, and their regulation in various species. Tribulus terrestris L., an annual medicinal herb of Zygophyllaceae family, has gained significant attention due to its diverse medicinal properties, including anti-inflammatory, antimicrobial, and anti-cancer effects ...
Parul Tyagi +3 more
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Plant Science, 1992
Abstract By selecting small cell aggregates, several cell lines of Dioscorea with different characteristics were established: colour, size of cell aggregates, growth, accumulation of carotenoids, diosgenin and phytosterols. The white-coloured lines accumulate larger amounts of diosgenin than the unselected cell suspension and the cream-coloured ...
Constantin Deliu +3 more
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Abstract By selecting small cell aggregates, several cell lines of Dioscorea with different characteristics were established: colour, size of cell aggregates, growth, accumulation of carotenoids, diosgenin and phytosterols. The white-coloured lines accumulate larger amounts of diosgenin than the unselected cell suspension and the cream-coloured ...
Constantin Deliu +3 more
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22R‐ but not 22S‐hydroxycholesterol is recruited for diosgenin biosynthesis
The Plant Journal, 2021SUMMARYDiosgenin is an important compound in the pharmaceutical industry and it is biosynthesized in several eudicot and monocot species, herein represented by fenugreek (a eudicot), and Dioscorea zingiberensis (a monocot). Formation of diosgenin can be achieved by the early C22,16‐oxidations of cholesterol followed by a late C26‐oxidation.
Chen Zhou +6 more
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Biosynthesis of diosgenin in Dioscorea tubers
Archives of Biochemistry and Biophysics, 1961Abstract The incorporation of radioacetate into diosgenin by homogenates of Dioscorea floribunda has been demonstrated by rigorous purification of the isolated sapogenin. Mevalonic acid is not incorporated into diosgenin to any significant extent under these conditions.
E, HEFTMANN, R D, BENNETT, J, BONNER
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[Pathway design and key enzyme analysis of diosgenin biosynthesis].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2021As a naturally occurring steroid sapogenin, diosgenin acts as the precursor of hundreds of steroid medicines, and thereby has important medicinal value. Currently, industrial production of diosgenin relies primarily on chemical extraction from plant materials.
Zhongyi, Sun +3 more
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Hormonal effects on diosgenin biosynthesis and growth in Dioscorea deltoidea tissue cultures
Phytochemistry, 1976Abstract Analysis of Dioscorea deltoidea tissue cultures grown in the presence of 2,4-D, indole-3-butyric acid, isopentenyladenine, benzyladenine and GA singly and in combination showed that the medium with 2,4-D most consistently favored diosgenin production. GA and high benzyladenine concentrations were toxic.
Jo G. Marshall, E.John Staba
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