Results 121 to 130 of about 1,104 (142)
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Plant Science, 2022
Diosgenin as a triterpene with numbers of pharmaceutical applications has been identified in Trigonella foenum-graceum. In this survey, in order to scale up the amount of diosgenin in Fenugreek as a promising alternative of yam, ∆24-reductase as a rate limiting enzyme in diosgenin biosynthesis pathway has been overexpressed by utilizing pBI121 ...
Sajad Rashidi Monfared +2 more
exaly +3 more sources
Diosgenin as a triterpene with numbers of pharmaceutical applications has been identified in Trigonella foenum-graceum. In this survey, in order to scale up the amount of diosgenin in Fenugreek as a promising alternative of yam, ∆24-reductase as a rate limiting enzyme in diosgenin biosynthesis pathway has been overexpressed by utilizing pBI121 ...
Sajad Rashidi Monfared +2 more
exaly +3 more sources
22R‐ but not 22S‐hydroxycholesterol is recruited for diosgenin biosynthesis
The Plant Journal, 2021SUMMARYDiosgenin is an important compound in the pharmaceutical industry and it is biosynthesized in several eudicot and monocot species, herein represented by fenugreek (a eudicot), and Dioscorea zingiberensis (a monocot). Formation of diosgenin can be achieved by the early C22,16‐oxidations of cholesterol followed by a late C26‐oxidation.
Chen Zhou +6 more
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Biosynthesis of diosgenin in Dioscorea tubers
Archives of Biochemistry and Biophysics, 1961Abstract The incorporation of radioacetate into diosgenin by homogenates of Dioscorea floribunda has been demonstrated by rigorous purification of the isolated sapogenin. Mevalonic acid is not incorporated into diosgenin to any significant extent under these conditions.
Erich Heftmann
exaly +3 more sources
Metabolic Engineering, 2023
Cholesterol serves as a key precursor for many high-value chemicals such as plant-derived steroidal saponins and steroidal alkaloids, but a plant chassis for effective biosynthesis of high levels of cholesterol has not been established. Plant chassis have significant advantages over microbial chassis in terms of membrane protein expression, precursor ...
Yuhua Li, Zheyong Xue
exaly +3 more sources
Cholesterol serves as a key precursor for many high-value chemicals such as plant-derived steroidal saponins and steroidal alkaloids, but a plant chassis for effective biosynthesis of high levels of cholesterol has not been established. Plant chassis have significant advantages over microbial chassis in terms of membrane protein expression, precursor ...
Yuhua Li, Zheyong Xue
exaly +3 more sources
Industrial Crops and Products, 2020
Abstract Induction of hairy roots stemmed from Agrobacterium rhizogenes transformation, is a key step to reach mass production of secondary metabolites in medicinal plants. Accordingly, this study is aimed to investigate potential impact of different A.
Sajad Rashidi Monfared, Amin Ebrahimi
exaly +2 more sources
Abstract Induction of hairy roots stemmed from Agrobacterium rhizogenes transformation, is a key step to reach mass production of secondary metabolites in medicinal plants. Accordingly, this study is aimed to investigate potential impact of different A.
Sajad Rashidi Monfared, Amin Ebrahimi
exaly +2 more sources
Gene
Next-generation sequencing (NGS) has revolutionized the analysis of specific genes, pathways, and their regulation in various species. Tribulus terrestris L., an annual medicinal herb of Zygophyllaceae family, has gained significant attention due to its diverse medicinal properties, including anti-inflammatory, antimicrobial, and anti-cancer effects ...
Parul Tyagi +2 more
exaly +3 more sources
Next-generation sequencing (NGS) has revolutionized the analysis of specific genes, pathways, and their regulation in various species. Tribulus terrestris L., an annual medicinal herb of Zygophyllaceae family, has gained significant attention due to its diverse medicinal properties, including anti-inflammatory, antimicrobial, and anti-cancer effects ...
Parul Tyagi +2 more
exaly +3 more sources
[Pathway design and key enzyme analysis of diosgenin biosynthesis].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2021As a naturally occurring steroid sapogenin, diosgenin acts as the precursor of hundreds of steroid medicines, and thereby has important medicinal value. Currently, industrial production of diosgenin relies primarily on chemical extraction from plant materials.
Zhongyi, Sun +3 more
openaire +1 more source
Plant Science, 1992
Abstract By selecting small cell aggregates, several cell lines of Dioscorea with different characteristics were established: colour, size of cell aggregates, growth, accumulation of carotenoids, diosgenin and phytosterols. The white-coloured lines accumulate larger amounts of diosgenin than the unselected cell suspension and the cream-coloured ...
Mircea Tamás, Cristina Dobrota
exaly +2 more sources
Abstract By selecting small cell aggregates, several cell lines of Dioscorea with different characteristics were established: colour, size of cell aggregates, growth, accumulation of carotenoids, diosgenin and phytosterols. The white-coloured lines accumulate larger amounts of diosgenin than the unselected cell suspension and the cream-coloured ...
Mircea Tamás, Cristina Dobrota
exaly +2 more sources
Acta Physiologiae Plantarum, 2016
Trillium govanianum Wall. ex D. Don, popularly known as Nagchhatri, is an important medicinal plant of northwestern Himalayas. No data exist on molecular characteristics of diosgenin biosynthesis, the main chemical component of T. govanianum. HPLC analysis revealed diosgenin content of 2.4 and 0.7% in hydrolyzed rhizome extracts of Chamba and Lahaul ...
Nikhil Malhotra, Hemant Sood
exaly +2 more sources
Trillium govanianum Wall. ex D. Don, popularly known as Nagchhatri, is an important medicinal plant of northwestern Himalayas. No data exist on molecular characteristics of diosgenin biosynthesis, the main chemical component of T. govanianum. HPLC analysis revealed diosgenin content of 2.4 and 0.7% in hydrolyzed rhizome extracts of Chamba and Lahaul ...
Nikhil Malhotra, Hemant Sood
exaly +2 more sources
New insights into diosgenin biosynthesis pathway and its regulation in
Abstract Introduction Throughout history, thousands of medicinal and aromatic plants have been widely utilised by people worldwide. Owing to them possessing of valuable compounds with little side effects in comparison with chemical drugs, herbs have been of interest to ...
Mohammad Mohammadi +4 more
openaire +2 more sources