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Diosgenin biosynthesis investigation in medicinal herb (Tribulus terrestris) by transcriptome analysis

Gene
Next-generation sequencing (NGS) has revolutionized the analysis of specific genes, pathways, and their regulation in various species. Tribulus terrestris L., an annual medicinal herb of Zygophyllaceae family, has gained significant attention due to its diverse medicinal properties, including anti-inflammatory, antimicrobial, and anti-cancer effects ...
Rajiv Ranjan, Shivangi Mathur
exaly   +3 more sources

Hormonal effects on diosgenin biosynthesis and growth in Dioscorea deltoidea tissue cultures

Phytochemistry, 1976
Abstract Analysis of Dioscorea deltoidea tissue cultures grown in the presence of 2,4-D, indole-3-butyric acid, isopentenyladenine, benzyladenine and GA singly and in combination showed that the medium with 2,4-D most consistently favored diosgenin production. GA and high benzyladenine concentrations were toxic.
Jo G. Marshall, E.John Staba
exaly   +2 more sources

Kinetics of cellular growth and diosgenin biosynthesis in Dioscorea caucasica cell suspensions, cultured in batch system

Plant Science, 1992
Abstract By selecting small cell aggregates, several cell lines of Dioscorea with different characteristics were established: colour, size of cell aggregates, growth, accumulation of carotenoids, diosgenin and phytosterols. The white-coloured lines accumulate larger amounts of diosgenin than the unselected cell suspension and the cream-coloured ...
Cristina Dobrota
exaly   +2 more sources

Expression analysis of steroid pathway genes revealed positive correlation with diosgenin biosynthesis in Trillium govanianum

Acta Physiologiae Plantarum, 2016
Trillium govanianum Wall. ex D. Don, popularly known as Nagchhatri, is an important medicinal plant of northwestern Himalayas. No data exist on molecular characteristics of diosgenin biosynthesis, the main chemical component of T. govanianum. HPLC analysis revealed diosgenin content of 2.4 and 0.7% in hydrolyzed rhizome extracts of Chamba and Lahaul ...
Hemant Sood   +2 more
exaly   +2 more sources

22R‐ but not 22S‐hydroxycholesterol is recruited for diosgenin biosynthesis

The Plant Journal, 2021
SUMMARYDiosgenin is an important compound in the pharmaceutical industry and it is biosynthesized in several eudicot and monocot species, herein represented by fenugreek (a eudicot), and Dioscorea zingiberensis (a monocot). Formation of diosgenin can be achieved by the early C22,16‐oxidations of cholesterol followed by a late C26‐oxidation.
Chen Zhou   +6 more
openaire   +2 more sources

[Pathway design and key enzyme analysis of diosgenin biosynthesis].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2021
As a naturally occurring steroid sapogenin, diosgenin acts as the precursor of hundreds of steroid medicines, and thereby has important medicinal value. Currently, industrial production of diosgenin relies primarily on chemical extraction from plant materials.
Zhongyi, Sun   +3 more
openaire   +1 more source

New insights into diosgenin biosynthesis pathway and its regulation in Trigonella foenum‐graecum L.

Phytochemical Analysis, 2019
Abstract Introduction Throughout history, thousands of medicinal and aromatic plants have been widely utilised by people worldwide. Owing to them possessing of valuable compounds with little side effects in comparison with chemical drugs, herbs have been of interest to ...
Mohammad Mohammadi   +4 more
openaire   +2 more sources

De novo Sequencing and Whole Transcriptome Analysis for Biosynthesis Pathway of Diosgenin in Pedalium murex L.: A Medicinal herb

2023
ABSTRACT Transcriptome-based investigations of candidate genes, critical pathways, and gene regulation in non- model species have been transformed by high-throughput RNA sequencing in different studies. Pedalium murex L. is one of the most important annual medicinal herbs of the
Parul Tyagi, Rajiv Ranjan
openaire   +1 more source

Identification and functional characterization of DzS3GT, a cytoplasmic glycosyltransferase catalyzing biosynthesis of diosgenin 3-O-glucoside in Dioscorea zingiberensis

Plant Cell, Tissue and Organ Culture (PCTOC), 2017
Dioscorea plants produce pharmaceutical diosgenin, which usually exists in plants in the form of saponins and has been a starting material for the production of steroids over seven decades. The first step of steroidal saponin biosynthesis from the corresponding aglycone is glycosylation by 3-O-sterol glycosyltransferase (S3GT), transferring the ...
Ting Ye   +6 more
openaire   +1 more source

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