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Biosynthesis and Translocation of Diosgenin in Costus speciosus

Journal of Plant Physiology, 1987
Summary Radio-actively labelled free and conjugated diosgenin was isolated from different parts such as stem, leaf, seeds, flowers, and rhizomes of Costus speciosus after feeding 14C mevalonate, diosgenin, and diosgenin glycoside through different parts in separate sets of experiments.
Anand Akhila, Madan M Gupta
exaly   +2 more sources

Metabolic engineering of the diosgenin biosynthesis pathway in Trigonella foenum-graceum hairy root cultures

Plant Science, 2022
Diosgenin as a triterpene with numbers of pharmaceutical applications has been identified in Trigonella foenum-graceum. In this survey, in order to scale up the amount of diosgenin in Fenugreek as a promising alternative of yam, ∆24-reductase as a rate limiting enzyme in diosgenin biosynthesis pathway has been overexpressed by utilizing pBI121 ...
Sajad Rashidi-Monfared   +2 more
exaly   +3 more sources

Transcriptome analysis of Dioscorea zingiberensis identifies genes involved in diosgenin biosynthesis

Genes and Genomics, 2017
Dioscorea zingiberensis is the main plant source of diosgenin, a precursor for the production of steroid hormones used in the pharmaceutical industry. The extraction process of diosgenin from D. zingiberensis can generate high-acid and high-strength wastewater on a large scale and can threaten the environment.
Xiaoyan Cao, Zhezhi Wang, Xiangmin Li
exaly   +2 more sources

Biosynthesis of diosgenin from 26-hydroxycholesterol in dioscorea floribunda

Phytochemistry, 1970
Abstract 26-Hydroxycholesterol-26- 14 C was converted by a Dioscorea floribunda plant to diosgenin. This result suggests that oxygenation at C-26 may be the first step in the biosynthesis of diosgenin from cholesterol. No diosgenin was formed from kryptogenin-26- 14 C by D.
Raymond D Bennett, Erich Heftmann
exaly   +2 more sources

Biosynthesis of diosgenin in Dioscorea tubers

Archives of Biochemistry and Biophysics, 1961
Abstract The incorporation of radioacetate into diosgenin by homogenates of Dioscorea floribunda has been demonstrated by rigorous purification of the isolated sapogenin. Mevalonic acid is not incorporated into diosgenin to any significant extent under these conditions.
E Heftmann, Erich Heftmann
exaly   +3 more sources

Improving diosgenin production and its biosynthesis in Trigonella foenum-graecum L. hairy root cultures

Industrial Crops and Products, 2020
Abstract Induction of hairy roots stemmed from Agrobacterium rhizogenes transformation, is a key step to reach mass production of secondary metabolites in medicinal plants. Accordingly, this study is aimed to investigate potential impact of different A.
Sajad Rashidi-Monfared   +2 more
exaly   +2 more sources

Deciphering the network of cholesterol biosynthesis in Paris polyphylla laid a base for efficient diosgenin production in plant chassis

Metabolic Engineering, 2023
Cholesterol serves as a key precursor for many high-value chemicals such as plant-derived steroidal saponins and steroidal alkaloids, but a plant chassis for effective biosynthesis of high levels of cholesterol has not been established. Plant chassis have significant advantages over microbial chassis in terms of membrane protein expression, precursor ...
Zheyong Xue
exaly   +3 more sources

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