Results 91 to 100 of about 4,688 (209)

Virtual Screening of Phytochemicals From Medicinal Plants as Promising PDE5 Inhibitors Against Erectile Dysfunction

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Phytochemicals from Algerian medicinal plants were virtually screened as potential phosphodiesterase‐5 (PDE5) inhibitors for erectile dysfunction therapy. Drug‐likeness and toxicity analyses identified catechin, ellagic acid, and rosmarinic acid as safe, bioavailable candidates.
Farouk Boudou, Alaeddine Berkane, Amal Belakredar, Ahcene Keziz, Huda Alsaeedi, Brian A. Murray, Mikhael Bechelany, Ahmed Barhoum   +7 more
wiley   +1 more source

Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice

Molecules, 2019
Colon cancer is the third most common type of cancer in the world. Diosmetin (Dis), a natural O-methylated flavone, has been reported to have anti-cancer effects against different types of cancer.
Sanaz Koosha, Zahurin Mohamed, Ajantha Sinniah, Mohammed A. Alshawsh   +3 more
doaj   +1 more source

Integrated green extraction of phenolic compounds and fermentable sugars from grapefruit peel using ultrasound and enzymatic hydrolysis

Journal of the Science of Food and Agriculture, Volume 106, Issue 3, Page 1839-1851, February 2026.
Abstract BACKGROUND Valorizing sugar‐rich food waste in biorefineries offers a sustainable route to bio‐based products. Grapefruit peel (GP), representing about 50% of the fruit's weight, is rich in sugars (soluble and insoluble) and polyphenols such as flavonoids.
María del Prado García‐Aparicio, María Castro‐Puyana, María Luisa Marina   +2 more
wiley   +1 more source

Development of HPLC Protocol and Simultaneous Quantification of Four Free Flavonoids from Dracocephalum heterophyllum Benth.

International Journal of Analytical Chemistry, 2015
Quantification of the four flavonoids, namely, luteolin, kaempferol, diosmetin, and chrysosplenetin, has been performed for the first time in 80% ethanolic extract of Dracocephalum heterophyllum B.
Sodik Rakhmonovich Numonov, Muhammad Nasimullah Qureshi, Haji Akber Aisa   +2 more
doaj   +1 more source

Antidiabetic Effects of Chamomile Flowers Extract in Obese Mice through Transcriptional Stimulation of Nutrient Sensors of the Peroxisome Proliferator-Activated Receptor (PPAR) Family [PDF]

, 2013
Given the significant increases in the incidence of metabolic diseases, efficient strategies for preventing and treating of these common disorders are urgently needed.
Abdel-Aziz, Heba, Freiwald, Anja, Kelber, Olaf, Kodelja, Vitam, Rousseau, Morten, Sauer, Sascha, Weidner, Christopher, Wowro, Sylvia J.   +7 more
core   +4 more sources

Neurocognitive improvement through plant food bioactives: A particular approach to Alzheimer's disease [PDF]

, 2017
Alzheimer’s disease (AD) is currently one of the most prevalent neurodegenerative disorders, directly related to increasing rates of morbidity and autonomy impairment between worldwide citizens. Social and demographical changes are direct contributors;
Ferreira, Isabel C.F.R., Martins, Natália   +1 more
core   +1 more source

Dioscin attenuates lupus nephritis in NZB/W F1 mice by decreasing NF-κB activation and NLRP3 inflammasome

Folia Histochemica et Cytobiologica
INTRODUCTION: Dioscin, a natural steroid saponin, has anticancer, anti-inflammatory, anti-hyperlipidemic, and glycemic capabilities. This study focused on dioscin roles and its related mechanisms in experimental lupus nephritis.
Yaling Xu, Han Li
doaj   +1 more source

Comparative Bioavailability of Two Diosmin Formulations after Oral Administration to Healthy Volunteers

Molecules, 2018
Diosmin is a flavonoid commonly found in citrus fruits, largely used as adjuvant treatment for circulatory disorders, including chronic venous insufficiency (CVI) and hemorrhoids.
Rosario Russo, Divya Chandradhara, Nunziatina De Tommasi   +2 more
doaj   +1 more source

DNA catabolites in triathletes: effects of supplementation with an aronia–citrus juice (polyphenols-rich juice) [PDF]

, 2016
In this study we analyzed whether our aronia–citrus juice (ACJ, the composition is based on a mixture of 95% citrus juice with 5% of Aronia melanocarpa juice), rich in polyphenols, and physical exercise had an effect on seven catabolites of DNA ...
Abellán, Ángel, Cejuela, Roberto, Ferreres, Federico, García-Flores, Libia Alejandra, Genieser, Hans-Gottfried, Gil-Izquierdo, Ángel, Martínez Sanz, José Miguel, Medina, Sonia   +7 more
core   +2 more sources

Diosmetin Delays In Vitro Aging of Porcine Oocytes by Improving Mitochondrial Function and Reducing Oxidative Stress

Animals
Oocyte quality is crucial for successful fertilization and subsequent embryonic development. Post-ovulatory aging leads to reduced oocyte quality and impaired embryogenesis, representing an unavoidable challenge in terms of certain assisted reproductive ...
Jia-Jun Ren, Xiu-Wen Yuan, Yu-Hao Zhang, Zi-Long Meng, Xing-Wei Liang, Nam-Hyung Kim, Yong-Nan Xu, Ying-Hua Li   +7 more
doaj   +1 more source