Results 221 to 230 of about 6,693 (273)

Influence of Hesperidin and Diosmin as Active Metabolites of Bioflavonoids on Venous Wall Remodeling in Primary Cultures of Endothelial Cells In Vitro

Journal of Venous Disorders
Objective. To study the effect of active metabolites of bioflavonoids (hesperetin and diosmetin) on remodeling markers (von Willebrand factor (vWF), platelet-endothelial cell adhesion molecule-1 (CD31), fibronectin (FN), vimentin (VIM), plasminogen ...
I. Suchkov, N. Mzhavanadze, R. Kalinin, A. V. Shchulkin, Y. Abalenikhina, E.Yu. Nazimova   +5 more
semanticscholar   +1 more source

Effects of the Flavonoid Diosmin on Post Exercise Muscle Soreness – A Randomized Controlled Trial

Journal of Dietary Supplements
Delayed-onset muscle soreness (DOMS) is hypothesized to be due to reversible damage at the cellular level, affecting both recreational and professional athletes.
Fabiana Cristina Barreiros da Cunha, G. B. Cortez, Isabela Mayer Pucci, Mariana Martins Silva, J. M. Borim, M. M. Bertozzi, J. L. Jacinto, Thacyana T. Carvalho, A. Aguiar, Juliano Casonatto, Eros O. Júnior, W. A. Verri, Sergio Marques Borghi   +12 more
semanticscholar   +1 more source

Evaluation of the Hepatoprotective Role of Diosmin in a Rat Model of Thioacetamide-induced Liver Fibrosis

Indian Journal of Animal Research
Background: Liver fibrosis is a progressive and potentially life-threatening condition characterized by excessive extracellular matrix accumulation that impairs hepatic function.
Ashraf Albrakati
semanticscholar   +1 more source

Spontaneous Intraventricular Hemorrhage Associated with Prolonged Diosmin Therapy

Neurocritical Care, 2011
The prevalent use of anticoagulation in a growing elderly population has led to an increasing incidence of intracerebral hemorrhage. Furthermore, the understanding of the interactions and adverse effects of oral anticoagulants when used with non-FDA approved drugs is limited.
Ramesh M, Kumar, Jamie J, Van Gompel, Regina, Bower, Alejandro A, Rabinstein   +3 more
openaire   +2 more sources

Role of carbonic anhydrase in the anti-inflammatory mechanism of diosmin and hesperidin in rats

Veterinaria México OA
Flavonoids such as diosmin and hesperidin produce antinociceptive and anti-inflammatory effects, potentially involving the inhibition of carbonic anhydrase (CA) as a mechanism of action.
Ady Xathziri Muñiz-Alquicira, Abel Zapata-Arenas, Ruth Bustamante-García, A. Gómez-Martínez, A. I. Carballo-Villalobos   +4 more
semanticscholar   +1 more source

Neuroprotective effects of biosynthesized silver nanoparticles using Diosmin in a rotenone-induced Parkinson’s disease rat model

International journal of zoology and applied biosciences
This study investigated the neuroprotective potential of silver nanoparticles (AgNPs) synthesized using Diosmin against rotenone-induced behavioral and motor impairments in a male Wistar rat model of Parkinson’s disease (PD).
A. Chinnaiyan
semanticscholar   +1 more source

DEVELOPMENT AND OPTIMIZATION OF NANOCOCHLEATE-BASED DIOSMIN CARRIERS FOR CANCER TREATMENT

Asian Journal of Pharmaceutical and Clinical Research
Objective: This study aimed to develop and optimize diosmin-loaded nanocochleates as a potential targeted delivery system for cancer therapy. Methods: A three-factor, three-level Box–Behnken design was employed to evaluate the effects of phospholipid ...
SARDAR SHELAKE, Shitalkumar Patil
semanticscholar   +1 more source

Study of the diosmin effect on red blood cell aggregation

Russian journal of biomechanics.
Angiological diseases include a large number of vascular pathologies, the treatment of which is characterized by special preventive approaches, surgical and conservative therapy, as well as rehabilitation. Despite the large flow of modern literature, the
Ina Sherozia, Maya Mantskava, N. Momtselidze, G. Kuchava, Giorgi Asatiani, Nugzar Pargalava, Alexandra Lyubimova   +6 more
semanticscholar   +1 more source

Diosmin and Other Venoactive Drugs: Mechanisms of Action, Current and Future Indications for Use

Journal of Venous Disorders
Venoactive Drugs (VADs) are an integral part of the conservative management of chronic venous diseases (CVD). The mechanism of action of these drugs is well-described.
D.V. Rylnikov, A.S. Khachatryan, E.A. Duenina, I. Zolotukhin   +3 more
semanticscholar   +1 more source

Rapid Analytical Method Development and Validation of RP-HPLC Method for Simultaneous Estimation of Diosmin and Hesperidin

International Journal of Pharmaceutical Science Invention
Developing a single analytical method for estimation of individual drug from a multidrug composition is a very challenging task. A simple, rapid, precise, and reliable reverse phase HPLC method was developed for the separation and estimation of Diosmin ...
Rajeshwari Rampally Rajeshwari Rampally, K. A. K. Ashwitha, E. S. E. Sateesh, B.Reshma B.Reshma, J.Jyothi J.Jyothi, K. K. K. Keerthana   +5 more
semanticscholar   +1 more source