Results 231 to 240 of about 6,693 (273)
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Comparative effectiveness of diosmin and hesperidin combination in patients with chronic venous insufficiency

Vrach
Objective. Comparative analysis of the therapeutic efficacy of the combined preparation of diosmin and hesperidin in two cohorts of patients with chronic venous insufficiency (CVI) stratified by body mass index. Material and methods.
S. Kseneva   +4 more
semanticscholar   +1 more source

The effect of diosmin against lead exposure in rats‡

Naunyn-Schmiedeberg's Archives of Pharmacology, 2019
In this study, the effect of diosmin against the adverse effects of lead exposure in rats was investigated. Wistar Albino race 40 male rats weighing 150-200 g 2-3 months were used. A total of 4 groups were assigned, one of which was control and the other 3 were trial groups.
Mehmet Bozdağ, Gökhan Eraslan
openaire   +2 more sources

Diosmin Prevents L‐NAME‐Induced Vascular Dysfunction and Remodeling in Rats via Suppressing the TGF‐β1 Downstream Signaling Pathway

Journal of food biochemistry
Background: Diosmin is a flavanone glycoside found in several citrus fruits’ pericarps, presenting several biological effects. The current research examined the effects and potential mechanisms of diosmin on vascular abnormalities in Sprague Dawley rats ...
Benchaporn Saengnak   +6 more
semanticscholar   +1 more source

Investigation of Ca2+ signaling induced by the flavonoid diosmin in glioblastoma cells and its potential implications in the treatment using the Ca2+ chelating agent BAPTA-AM

Toxicology Mechanisms and Methods
Flavonoids, found in fruits and vegetables, can potentially prevent brain diseases. Diosmin (diosmetin-7-O-rutinoside), a flavonoid, exhibits various pharmacological activities, but its impact on calcium ion (Ca2+) signaling and the associated mechanisms
Lyh-Jyh Hao   +4 more
semanticscholar   +1 more source

A pharmacokinetic study of 3H-diosmine.

Arzneimittel-Forschung, 1977
A pharmacokinetic study of 3H-labelled 7-rhamnoglycoside of 5,7,3'-trihydroxy-4'-methoxyflavone (3H-diosmine) administered both i.v. and orally, shows the great ease with which it is absorbed in digestion. A very sharp difference in elimination between the two modes of treatment must be associated with a difference in metabolism.
J, Oustrin, M J, Fauran, L, Commanay
openaire   +1 more source

Inhibition Effect of Diosmin Flavanoid on Some Metabolic Enzymes and Investigation of Antioxidant Properties

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Diosmin is a natural flavonoid obtained by dehydrating flavanone glycoside hesperidin. This study evaluated the inhibition effects of diosmin flavonoid on human carbonic anhydrases (hCA I and hCA II) and acetylcholinesterase (AChE) enzymes, which are ...
Neslihan Balcı
semanticscholar   +1 more source

Diosmin/hesperidin

Reactions Weekly, 2022
openaire   +1 more source

[Studies on pharmacokinetics of diosmin in rats].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008
To establish a HPLC method for the determination of diosmin in Rats plasma and to study the pharmacokinetics of diosmin in Rats.Rats were given diosmin with 3 doses as 225, 325, 425 mg x kg(-1). Blood samples were collected at different times after oral administration. The plasma concentration of diosmin was determined by HPLC, and the pharmacokinetics
Ying-Li, Ma, Chao, Ma
openaire   +1 more source

Diosmin fromCampanula patula

Chemistry of Natural Compounds, 1978
L. S. Teslov, G. G. Zapesochnaya
openaire   +1 more source

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