Global Health Action, 2013 Background: A public health intervention program with active involvement of local related stakeholders was piloted in the Bien Hoa dioxin hotspot (2007–2009), and then expanded to the Da Nang dioxin hotspot in Vietnam (2009–2011).
Vu-Anh Le +2 more
doaj +1 more source
BMC Genomics, 2010 Background The major toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) appear to result from dysregulation of mRNA levels mediated by the aryl hydrocarbon receptor (AHR). Dioxin-like chemicals alter expression of numerous genes in liver, but it
Okey Allan B +4 more
doaj +1 more source
The Seveso accident: A look at 40 years of health research and beyond
Environment International, 2018 A 1976 chemical factory explosion near Seveso, Italy exposed residents to high levels of 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD or dioxin). Dioxin is a known human carcinogen and potent endocrine disruptor. It is highly lipophilic and has a long half-
Brenda Eskenazi +5 more
doaj +1 more source
Assessment of the feed additive consisting of <i>Enterococcus lactis</i>DSM 10663 NCIMB 10415 (Oralin®) for calves for rearing, piglets, chickens for fattening, turkeys for fattening, cats and dogs for the renewal of its authorisation (Chevita Tierarzneimittel GmbH). [PDF]
EFSA JAbstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of authorisation of the additive Oralin®, a preparation containing viable cells of Enterococcus lactis DSM 10663 (formerly identified as Enterococcus faecium), as a zootechnical feed additive for ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
europepmc +2 more sources
Persistent organic pollutant burden, experimental POP exposure and tissue properties affect metabolic profiles of blubber from grey seal pups [PDF]
, 2018 Persistent organic pollutants (POPs) are toxic, ubiquitous, resist breakdown, bioaccumulate in living tissue and biomagnify in food webs. POPs can also alter energy balance in humans and wildlife.
Bennett, Kimberley A. +5 more
core +4 more sources
Environmental Pollutant Hexachlorobenzene Induces Hypertension In a Rat Model [PDF]
, 2018 Hexachlorobenzene (HCB) is a dioxin-like environmental pollutant, widely distributed in the environment. New research links exposure to high levels of persistent organic environmental toxicants to cardiovascular disease, however little is known about the
Alvarez, Laura +8 more
core +1 more source
Novel Therapeutic Targets for the Treatment of Atopic Dermatitis
Biomedicines, 2023 Atopic dermatitis (AD) is a chronic inflammatory skin disease that significantly impacts quality of life. The pathogenesis of AD is a complex combination of skin barrier dysfunction, type II immune response, and pruritus. Progress in the understanding of
Gaku Tsuji +5 more
doaj +1 more source
Dioxins are toxic by-products of industrial combustion processes, characterized by being colorless, odorless, water-insoluble, and not commercially produced. These compounds, including both dioxins and furans, exhibit various properties and toxicity levels. Due to their high lipophilicity, they resist metabolic and environmental degradation, leading to
Muberra Ozcan
+4 more sources
Urinary amino acid alterations in 3-year-old children with neurodevelopmental effects due to perinatal dioxin exposure in Vietnam: a nested case-control study for neurobiomarker discovery. [PDF]
PLoS ONE, 2015 In our previous study of 3-year-old children in a dioxin contamination hot spot in Vietnam, the high total dioxin toxic equivalent (TEQ-PCDDs/Fs)-exposed group during the perinatal period displayed lower Bayley III neurodevelopmental scores, whereas the ...
Muneko Nishijo +10 more
doaj +1 more source
PLoS ONE, 2012 Environmental compounds can promote epigenetic transgenerational inheritance of adult-onset disease in subsequent generations following ancestral exposure during fetal gonadal sex determination.
Mohan Manikkam +3 more
doaj +1 more source