Results 141 to 150 of about 8,444 (178)

Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing. [PDF]

Acta Neuropathol, 2015
Schludi MH, May S, Grässer FA, Rentzsch K, Kremmer E, Küpper C, Klopstock T, German Consortium for Frontotemporal Lobar Degeneration, Bavarian Brain Banking Alliance, Arzberger T, Edbauer D.   +10 more
europepmc   +1 more source

Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72. [PDF]

Acta Neuropathol Commun, 2014
Davidson YS, Barker H, Robinson AC, Thompson JC, Harris J, Troakes C, Smith B, Al-Saraj S, Shaw C, Rollinson S, Masuda-Suzukake M, Hasegawa M, Pickering-Brown S, Snowden JS, Mann DM.   +14 more
europepmc   +1 more source

RAN translation of C9orf72-related dipeptide repeat proteins in zebrafish recapitulates hallmarks of amyotrophic lateral sclerosis and identifies hypothermia as a therapeutic strategy

Burrows DJ, McGown A, Abduljabbar O, Castelli LM, Shaw PJ, Hautbergue GM, Ramesh TM.   +6 more
europepmc   +1 more source

The telomeric valine-arginine dipeptide repeat protein changes state to diffuse staining in mitosis and represses in vitro translation. [PDF]

Proc Natl Acad Sci U S A
Al-Turki T, Mantri V, Willcox S, Mills CA, Herring LE, Cho SJ, Lee H, Meyer C, Anton ES, Griffith JD.   +9 more
europepmc   +1 more source

Decoding the functions of nuclear speckles in neurodegeneration. [PDF]

Trends Neurosci
Chen X, Zhu B.
europepmc   +1 more source

MARK2 regulates C9orf72 repeat-associated non-AUG translation. [PDF]

Proc Natl Acad Sci U S A
Lu YN, Li X, Hayes L, Zhao XF, Wang J.
europepmc   +1 more source

<i>C9orf72</i> poly(glycine-alanine) knock-in mice exhibit mild rotarod and proteomic changes consistent with amyotrophic lateral sclerosis/frontotemporal dementia. [PDF]

Brain Commun
Milioto C, Carcolé M, Zanovello M, Ahmed M, Nirujogi RS, Biggs D, Roberts MJ, Schweers K, Cammack AJ, Marchi PM, Katona E, Glaria I, Santos A, Devoy A, Fratta P, Alessi DR, Davies B, Greensmith L, Fisher EMC, Isaacs AM.   +19 more
europepmc   +1 more source

Tandem repeats in human brain evolution and disease susceptibility. [PDF]

Mol Cells
Lee H, An JY.
europepmc   +1 more source

A fly model of SCA36 reveals combinatorial neurotoxicity of hexanucleotide and dipeptide repeats. [PDF]

PLoS Genet
Hsiao CT, Fu SJ, Guo TN, Lin CC, Tsao YJ, Chang W, Liao YC, Hashimoto M, Huang SY, Lee YC, Yu CH, Chan CC.   +11 more
europepmc   +1 more source