Results 51 to 60 of about 12,907 (206)

The study of a new and specific proline cleaving peptidase from bovine serum [PDF]

, 2003
Prolyl oligopeptidase is a serine peptidase characterised by oligoendopeptidase activity. Definitive evidence for the discrete biological role of prolyl oligopeptidase remains unknown, though its role in the maturation and degradation of peptide hormones
Collins, Patrick
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De-novo Design of Some New Lead Compounds as Dipeptidyl Peptidase-IV Inhibitors [PDF]

, 2017
The use of dipeptidyl peptidase-IV (DPP-IV) inhibitors has been an established practice in the management of type-2 diabetes mellitus in recent years.
Jain, Sanmati K, Ghode, Piyush
core   +2 more sources

The multiple actions of dipeptidyl peptidase 4 (DPP-4) and its pharmacological inhibition on bone metabolism: a review

Diabetology & Metabolic Syndrome
Background Dipeptidyl peptidase 4 (DPP-4) plays a crucial role in breaking down various substrates. It also has effects on the insulin signaling pathway, contributing to insulin resistance, and involvement in inflammatory processes like obesity and type ...
L. M. Pechmann, F. I. Pinheiro, V. F. C. Andrade, C. A. Moreira   +3 more
doaj   +1 more source

Identification of phytoconstituents from Houttuynia cordata Thunb. as dipeptidyl peptidase-IV and sodium glucose cotransporter 2 inhibitors guided by molecular docking

Phytomedicine Plus
Purpose: Houttuynia cordata Thunb. is an edible medicinal herb belonging to the Saururaceae family. Although the effects of the plant extracts on several diabetic-related parameters have been documented in the past, there is no documentation of the ...
Careen Liza Pakyntein, Daiahun Thabah, Anita Kumari Rai, Donkupar Syiem   +3 more
doaj   +1 more source

Phosphoinositide-specific phospholipase C inhibition data using the dipeptidyl peptidase-IV inhibitors K-579 and LAF-237 [PDF]

, 2014
Data set for Fig 2 in the main article, describing the inhibition of Phosphoinositide-specific phospholipase C inhibition using the dipeptidyl peptidase-IV inhibitors K-579 and LAF-237.
Mouparna Dutta (300157), Bjarni Ásgeirsson (120419), Abhaya M. Dandekar (161322), Félix M. Goñi (442028), Masataka Oda (159724), Anindya S. Ghosh (498808), Sandeep Chakraborty (120418), Basuthkar J. Rao (110315), Adela Rendón-Ramírez (442027), Ravindra Venkatramani (465945)   +9 more
core   +1 more source

Fast Skeletal Muscle Troponin and Tropomyosin as a Dietary Source of Antidiabetic and Antihypertensive Bioactive Peptides: An In Silico Study

Vitae, 2023
Background : The nutraceutical properties of food hydrolysates rely on multiple biochemical interactions involving the modulation of enzymes and cellular receptors.
Jorge Andrés Barrero, María Alejandra Barrero, Angélica María González Clavijo, Claudia Marcela Cruz   +3 more
doaj   +1 more source

Two-Year Therapeutic Efficacy and Safety of Initial Triple Combination of Metformin, Sitagliptin, and Empagliflozin in Drug-Naïve Type 2 Diabetes Mellitus Patients [PDF]

Diabetes & Metabolism Journal
Background We investigated the long-term efficacy and safety of initial triple therapy using metformin, a dipeptidyl peptidase-4 inhibitor, and a sodium-glucose cotransporter-2 inhibitor, in patients with type 2 diabetes mellitus. Methods We enrolled 170
Young-Hwan Park, Minji Sohn, So Yeon Lee, Soo Lim   +3 more
doaj   +1 more source

Identification and Characterization of Dipeptidyl Peptidase-IV Inhibitory Peptides from Oat Proteins

Foods, 2022
In this study, flavourzyme, papain, neutrase, and alcalase, as well as gastrointestinal digestion simulated with pepsin and pancreatin, were used to hydrolyze oat protein, and the dipeptidyl peptidase-IV (DPP-IV) inhibitory activities of the oat protein ...
Wei Wang, Xiaoqing Liu, Yiju Li, Haixi You, Zhipeng Yu, Liying Wang, Xuebo Liu, Long Ding   +7 more
doaj   +1 more source

Interaction of a new copper(II) complex by bovine serum albumin and dipeptidyl peptidase-IV [PDF]

, 2019
Dipeptidyl peptidase-IV (DPP-IV) is one of the mammalian serine proteases participated in the pathogenesis of diseases and DPP-IV inhibitors are now widely used as antidiabetic drugs.
Zorlu, Y., Zeytünlüoğlu, Ali, İnci, D., Köseler, Aylin, Aydın, R.   +4 more
core   +3 more sources

Dipeptidyl Peptidase-Iv Inhibitors: An Evolving Treatment for Type 2 Diabetes from the Incretin Concept [PDF]

, 2008
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide (GLP-1) are the 2 major incretin hormones released after meals to enhance glucose-stimulated insulin secretion.
CHYAN, YAU-JAN;CHUANG, LEE-MING, 錢瑤珍;莊立民   +1 more
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