Results 1 to 10 of about 134,595 (257)
Nature Reviews Disease Primers, 2019 Diphtheria is a potentially fatal infection mostly caused by toxigenic Corynebacterium diphtheriae strains and occasionally by toxigenic C. ulcerans and C. pseudotuberculosis strains. Diphtheria is generally an acute respiratory infection, characterized by the formation of a pseudomembrane in the throat, but cutaneous infections are possible.
Igor Mokrousov +2 more
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Autochthonous outbreak of respiratory diphtheria caused by Corynebacterium diphtheriae, Germany, September 2024 [PDF]
EurosurveillanceIn September 2024, a school-aged child (P1), unvaccinated against diphtheria, was hospitalised with severe respiratory diphtheria caused by toxigenic Corynebacterium diphtheriae. P1 subsequently died from the disease.
Andreas Sing
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Open Research Europe, 2023 Background: In industrialised countries diphtheria is a rare but still life-threatening disease with a recent increase in cases due to migration and zoonotic aspects.
Anja Berger +3 more
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Determination of Diphtheria Toxin in Bacterial Cultures by Enzyme Immunoassay
Diagnostics, 2022 Since diphtheria toxin (DT) is the main virulence factor of Corynebacterium diphtheriae and C. ulcerans, the detection of DT in corynebacterial cultures is of utmost importance in the laboratory diagnosis of diphtheria.
Maria A. Simonova +6 more
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Canada Communicable Disease Report, 2021 Background: Canada has maintained a low incidence of toxigenic diphtheria since the 1990s, supported by continued commitment to publicly funded vaccination programs.
Dolly Lin +3 more
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IMMUNOBIOLOGY OF DIPHTHERIA. RECENT APPROACHES FOR THE PREVENTION, DIAGNOSIS, AND TREATMENT OF DISEASE [PDF]
Biotechnologia Acta, 2013 Diphtheria is a highly contagious life-threatening disease caused by the toxi genic strains of Corynebacterium diphtheria, which are transformed by a bacteriophage carrying the toxin gene.
D. V. Kolybo +6 more
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Assay of Diphtheria Vaccine Potency by Intradermal Challenge Test
Эпидемиология и вакцинопрофилактика, 2023 Relevance. Modern identifying potency (immunogenicity) of diphtheria toxoid tests are based on determining immunized animals resistance for administration challenge toxin or evaluation of protective antibodies level in serum.
E. I. Komarovskaya, О. V. Perelygyna
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Evaluation of the immune response to diphtheria and tetanus toxoids by the serological methods
Биопрепараты: Профилактика, диагностика, лечение, 2023 Scientific relevance. Currently, two types of methods are used to evaluate the potency of diphtheria and tetanus toxoids: the gold standard, which involves administering toxins to immunised animals, and serological methods, which involve quantifying ...
Е. I. Komarovskaya, A. A. Soldatov
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BIOLOGICAL PROPERTIES AND MEDICAL APPLICATION OF DIPHTHERIA TOXIN DERIVATIVES [PDF]
Biotechnologia Acta, 2018 The aim of the review was to analyze the literature data related to the application of a variety of diphtheria toxin derivatives. Although studies of the diphtheria toxin interaction with sensitive and resistant mammalian cells have been held for a ...
Manoilov K.Y.
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Biotechnology & Biotechnological Equipment, 2020 Infections caused by Campylobacter spp. continue to be a serious health burden worldwide. The importance of Campylobacter jejuni/coli for the development of acute gastroenteritis in Bulgaria has not been studied well yet, especially in early childhood ...
Maria Pavlova +5 more
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