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Diphtheria is a potentially fatal infection mostly caused by toxigenic Corynebacterium diphtheriae strains and occasionally by toxigenic C. ulcerans and C. pseudotuberculosis strains. Diphtheria is generally an acute respiratory infection, characterized by the formation of a pseudomembrane in the throat, but cutaneous infections are possible.
Sharma, Naresh Chand+5 more
semanticscholar +9 more sources
A population-level analysis of armed conflict and diphtheria at the subnational level in the WHO African Region 2017-2024. [PDF]
Background Diphtheria has been re-emerging around the world at alarming rates, raising concerns about emergency preparedness, especially when global supplies of life-saving diphtheria antitoxin are insufficient.
O'Sullivan T, Keegan LT.
europepmc +2 more sources
Humoral Immunity to Measles, Mumps, Rubella, Diphtheria, Tetanus and Pertussis After Cancer Treatment in Children [PDF]
ABSTRACT Background Treatment for pediatric malignancies has distinct effects on the immune system. Aims Our aim was to measure humoral immunity to measles, mumps and rubella (MMR), and diphtheria, tetanus and acellular pertussis (DTaP) vaccines after pediatric cancer treatment.
Susanna Sundell+6 more
wiley +2 more sources
Background: Diphtheria remains a health problem, especially in developing countries. In November 2017, the Indonesian Ministry of Health stated that there was a diphtheria outbreak in Indonesia.
Iwan Muhamad Ramdan+3 more
doaj +2 more sources
Treg Control of CD80/CD86 Expression Mediates Immune System Homeostasis [PDF]
The acute depletion of Tregs induces activation of APCs and Tconvs, eventually leading to autoimmune disease. This activation could only be prevented by the blockade of CD80/CD86, so CD80/CD86‐CTLA‐4 interactions appear to be the most important Treg suppressor mechanism in the maintenance of immune homeostasis in the steady state.
Yong‐Hee Kim+2 more
wiley +2 more sources
DIPHTHERIA AND PSEUDO-DIPHTHERIA. [PDF]
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Park, W.-M. Hallock, Beebe, Alfred L.
openaire +6 more sources
Two diphtheria outbreaks occurred in a Swiss asylum center from July to October 2022, one is still ongoing. Outbreaks mainly involved minors and included six symptomatic respiratory diphtheria cases requiring antitoxin.
Jacob Kofler+13 more
semanticscholar +1 more source
New Corynebacterium Species with the Potential to Produce Diphtheria Toxin
Only three Corynebacterium species are known to produce a lethal exotoxin called diphtheria toxin. These are C. diphtheriae, C. ulcerans and C. pseudotuberculosis.
Marta Prygiel+5 more
semanticscholar +1 more source
Determination of Diphtheria Toxin in Bacterial Cultures by Enzyme Immunoassay
Since diphtheria toxin (DT) is the main virulence factor of Corynebacterium diphtheriae and C. ulcerans, the detection of DT in corynebacterial cultures is of utmost importance in the laboratory diagnosis of diphtheria.
Maria A. Simonova+6 more
doaj +1 more source