Results 11 to 20 of about 8,879 (193)

Recurrent diphtheria outbreaks in Nigeria: A review of the underlying factors and remedies

Immunity, Inflammation and Disease, 2023
Introduction The introduction of the diphtheria−tetanus−pertussis (DTP) vaccine into childhood immunization programs resulted in its widespread elimination in high‐income countries. However, Nigeria is currently experiencing an outbreak.
Nasir Abdulrasheed, Lukman Lawal, Abdulazeez B. Mogaji, Ahmed O. Abdulkareem, Abdulrahman K. Shuaib, Sodiq G. Adeoti, Opeyemi P. Amosu, Abdulmujeeb O. Muhammad‐Olodo, Abdulwahab O. Lawal, Tawakalitu A. Jaji, Toufik Abdul‐Rahman   +10 more
doaj   +2 more sources

Diphtheria Antitoxin Levels in the Netherlands: a Population-Based Study

Emerging Infectious Diseases, 1999
In a population-based study in the Netherlands, diphtheria antitoxin antibodies were measured with a toxin-binding inhibition assay in 9,134 sera from the general population and religious communities refusing vaccination.
Hester E. de Melker, G.A.M. Berbers, N.J.D. Nagelkerke, M.A.E. Conyn-van Spaendonck   +3 more
doaj   +2 more sources

Diphtheria Carriage

Эпидемиология и вакцинопрофилактика, 2018
The diphtheria carriage is a asympthomatic colonization of oro- and nasopharynx by toxigenic and nontoxigenic Corynebacterium diphtheriae. The carriage of toxigenic strains prevents a complete eradication of diphtheria infection in spite of mass toxoid ...
N. N. Kostyukova, V. A. Bechalo
doaj   +3 more sources

Validation of an ELISA-type immune-enzymatic test to quantify levels of diphtheria antitoxin in human serum

Revista Habanera de Ciencias Médicas, 2018
Introduction: Diphtheria still persists in many countries. In Cuba, studies conducted in different age groups have demonstrated that there are non-protective levels of diphtheria antitoxin in the population, so it is necessary to have methods that allow ...
Cira Virgen Rodríguez Pelier, Yaíma Zúñiga Rosales, Bárbara Torres Rives, Minerva Matarán Valdéz   +3 more
doaj   +2 more sources

Diphtheria-neutralizing antibody levels in healthy adults from Rio de Janeiro, Brazil

Memorias do Instituto Oswaldo Cruz, 2006
In Brazil, until 2004, the immunization policy against diphtheria involved childhood vaccination with no official routine booster dose administered after 15 years of age.
Fabricia Pires Pimenta, Paulo Vieira Damasco, José Cerbino Neto, Guilherme Santoro Lopes, Raphael Hirata Jr, Lucimar Gonçalves Milagres, Ana Luíza Mattos-Guaraldi   +6 more
doaj   +2 more sources

Determination of low tetanus or diphtheria antitoxin titers in sera by a toxin neutralization assay and a modified toxin-binding inhibition test

Brazilian Journal of Medical and Biological Research, 2007
A method for the screening of tetanus and diphtheria antibodies in serum using anatoxin (inactivated toxin) instead of toxin was developed as an alternative to the in vivo toxin neutralization assay based on the toxin-binding inhibition test (TOBI test).
M.H. Sonobe, A.G. Trezena, F.B. Guilhen, V.L. Takano, F. Fratelli, D. Sakauchi, J.F. Morais, S.M.A. Prado, H.G. Higashi   +8 more
doaj   +1 more source

Clinical presentation and predictors of hospital mortality of diphtheria in Nigeria, July 2023 to April 2024: a single-center study [PDF]

BMC Infectious Diseases
Background Despite recurrent outbreaks of diphtheria in Nigeria, there is a lack of in-depth analysis of hospitalization outcomes. Herein, we describe the sociodemographic, clinical, and laboratory features associated with hospitalization outcomes ...
Abdurrazzaq Alege, Olayinka Rasheed Ibrahim, Rasheedat Mobolaji Ibraheem, Olajide Aladesua, Abubakar Sani Lugga, Yunusa Yusuf Yahaya, Abdallah Sanda, Bello Muhammed Suleiman   +7 more
doaj   +2 more sources

Diphtheria outbreak in Somalia: a weekly sitrep on the recent health crisis-2025 [PDF]

Tropical Medicine and Health
The global diphtheria incidence has fallen following widespread use of the diphtheria–tetanus–pertussis (DTP) vaccine; pockets of low coverage and disrupted health services continue to fuel outbreaks.
Saadaq Adan Hussein, Marian Muse Osman, Mohamed Mohamoud Hassan, Yahye Sheikh Abdulle Hassan, Abdirahman Aden Hussein, Rage Adem, Mohamed M. Ali Fuje, Ayan Nur Ali, Abdinur Hussein Mohamed, Khadar Hussein Mohamud, Abdirahman Moallim Ibrahim, Mohamed Farah Yusuf, Abdinur Adan Hussein, Abdullahi Mohamed Mohamud, AbdulJalil Abdullahi Ali   +14 more
doaj   +2 more sources

Passive Immunisation in the Treatment of Infectious Diseases Related to Highly Potent Bacterial Toxins [PDF]

Biomedicines
The discovery of microbial toxins as the primary factors responsible for disease manifestations and the discovery that these toxins could be neutralised by antitoxins are linked to the birth of immunology. In the late 19th century, the serum or plasma of
Marta Prygiel, Ewa Mosiej, Karol Wdowiak, Aleksandra Anna Zasada   +3 more
doaj   +2 more sources

A population-level analysis of armed conflict and diphtheria at the subnational level in the WHO African Region 2017–2024 [PDF]

BMC Global and Public Health
Background Diphtheria has been re-emerging around the world at alarming rates, raising concerns about emergency preparedness, especially when global supplies of life-saving diphtheria antitoxin are insufficient.
Tierney O’Sullivan, Lindsay T. Keegan
doaj   +2 more sources