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Some new observations on diphtheria toxin and antitoxin.

open access: green, 1951
C. G. Pope   +3 more
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Crystallization of diphtheria toxin

Journal of Molecular Biology, 1991
Two new crystal forms (forms III and IV) have been grown of diphtheria toxin (DT), which kills susceptible cells by catalyzing the ADP-ribosylation of elongation factor 2, thereby stopping protein synthesis. Forms III and IV diffract to 2.3 A and 2.7 A resolution, respectively.
G, Fujii   +3 more
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Diphtheria Toxin and the Diphtheria-Toxin Receptor

2000
The discovery of diphtheria toxin from culture medium of Corynehacterium diphtheriae was one of the greatest discoveries in medical history. Since this epoch-making change in medicine, diphtheria toxin has been studied, first to prevent disease and later to understand the pathogenic mechanism at the molecular level. A number of important discoveries in
T. Umata, K. D. Sharma, E. Mekada
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Diphtheria Toxin

The Journal of Immunology, 1935
Summary Semi-synthetic medium for toxin production by C. diphtheriae is quite convenient in preparation and also economical. Toxin produced in the medium described above is as potent as that produced in the ordinary-infusion bouillon. Anatoxin prepared from this toxin does not flocculate when mixed with graded amounts of antitoxin and ...
K Ando, T Komiyama
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On the formation of diphtheria toxin in saliva byC. diphtheriae

Antonie van Leeuwenhoek, 1953
1. The iron contents of a number of saliva samples were determined. The iron contents found varied from 0.10–0.61 γ per g of saliva, while in some cases the iron quantity present was so small that it could not be determined. 2. These iron contents are of the same quantitative order as the concentrations of this element in the various ...
A, TASMAN, L, SMITH
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