Results 11 to 20 of about 79,524 (248)

Structural perturbation of diphtheria toxoid upon adsorption to aluminium hydroxide adjuvant

open access: yesVaccine, 2012
Aluminium-containing adjuvants are often used to enhance the potency of vaccines. In the present work we studied whether adsorption of diphtheria toxoid to colloidal aluminium hydroxide induces conformational changes of the antigen. Diphtheria toxoid has
Gideon Kersten   +2 more
exaly   +3 more sources

SYNTHESIS AND CHARACTERIZATION OF POLY(D,L-LACTIC-CO-GLYCOLIC)ACID MICROPARTICLES LOADED BY DIPHTHERIA TOXOID [PDF]

open access: yesBiotechnologia Acta, 2018
The aim of the study was to synthesize poly(D,L-lactide-co-glycolide) particles — PLGA and obtain their complexes with a non-toxic diphtheria toxin recombinant fragment subunit B fused with enhanced green fluorescent protein EGFP-SubB; to characterize ...
T. O. Chudina   +2 more
doaj   +2 more sources

Postbooster Antibodies from Humans as Source of Diphtheria Antitoxin

open access: yesEmerging Infectious Diseases, 2016
Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might
Jesús F. Bermejo-Martin   +5 more
doaj   +2 more sources

Diphtheria Carriage [PDF]

open access: yesЭпидемиология и вакцинопрофилактика, 2018
The diphtheria carriage is a asympthomatic colonization of oro- and nasopharynx by toxigenic and nontoxigenic Corynebacterium diphtheriae. The carriage of toxigenic strains prevents a complete eradication of diphtheria infection in spite of mass toxoid ...
N. N. Kostyukova, V. A. Bechalo
doaj   +2 more sources

Additional Recommendations for Use of Tetanus Toxoid, Reduced-Content Diphtheria Toxoid, and Acellular Pertussis Vaccine (Tdap)

open access: yesPediatrics, 2011
The American Academy of Pediatrics and the Centers for Disease Control and Prevention are amending previous recommendations and making additional recommendations for the use of tetanus toxoid, reduced-content diphtheria toxoid, and acellular pertussis ...
M. Brady   +12 more
semanticscholar   +2 more sources

Improved Specificity of a Multiplex Immunoassay for Quantitation of Anti-Diphtheria Toxin Antibodies with the Use of Diphtheria Toxoid

open access: yesClinical and Vaccine Immunology, 2011
A nonspecific binding of antibodies to diphtheria toxin, especially in adult serum samples, was observed in our diphtheria-tetanus-pertussis multiplex immunoassay (DTaP4 MIA). This can be significantly reduced by the use of diphtheria toxoid, achieving a
P. V. van Gageldonk   +3 more
semanticscholar   +2 more sources

Proteomics of diphtheria toxoid vaccines reveals multiple proteins that are immunogenic and may contribute to protection of humans against Corynebacterium diphtheriae. [PDF]

open access: yesVaccine, 2019
Introduced for mass immunization in the 1920s, vaccines against diphtheria are among the oldest and safest vaccines known. The basic principle of their production is the inactivation of purified diphtheria toxin by formaldehyde cross-linking, which ...
Jens Möller   +11 more
semanticscholar   +2 more sources

Guillain-Barré syndrome after tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine: a case report [PDF]

open access: yesJournal of Medical Case Reports, 2011
Introduction The association of Guillain-Barré syndrome with vaccination has been described in the literature; it is infrequent and controversial. An association with swine influenza, influenza, hepatitis and tetanus vaccination has been documented in ...
Ammar Hussam
doaj   +3 more sources

Adverse Effects of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine in 6- to 7-Year-Old Children

open access: yesPediatrics and Neonatology, 2011
Although the safety profile of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccines in adolescents and adults has been documented, few data have reported about their adverse events in children.
Sung-Hsi Wei   +4 more
doaj   +3 more sources

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