Results 11 to 20 of about 17,483 (231)

Polyanhydride-Based Microparticles for Programmable Pulsatile Release of Diphtheria Toxoid (DT) for Single-Injection Self-Boosting Vaccines. [PDF]

Adv Mater
This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high antigen recovery and is guided by machine learning for tunability. In vivo results show immune responses comparable to multi‐dose regimens, highlighting its potential
Zhang L, Xiao R, Gao W, Garcia J, Pan X, Daristotle JL, Forster T, Han J, Chaddah M, Varshney D, Menon N, McHugh KJ, Pedretti BJ, Yeo JY, Yang X, MacDonald S, Langer R, Jaklenec A.   +17 more
europepmc   +2 more sources

Seroprevalence of anti-diphtheria toxoid antibody and implications for vaccination policy in Vietnam’s South-central coast: a cross-sectional study [PDF]

BMC Infectious Diseases
Background Diphtheria is a re-emerging infectious disease and public health concern worldwide and in Vietnam with increasing cases in recent years. This study aimed to assess the anti-diphtheria toxoid antibodies status in Khanh Hoa Province and identify
Hoang Thieu Le, Thai Hung Do, The Anh Dao, Tien Thanh Hoang, Bao Trieu Nguyen, Thuy Lien Le, Dinh Luong Nguyen, Lay-Myint Yoshida, Xuan Huy Le, Hong Quan Le, That Toan Ton, Min Jin Ha   +11 more
doaj   +2 more sources

Seroprevalence of diphtheria toxoid IgG antibodies in the Malaysian population [PDF]

BMC Infectious Diseases, 2021
Background Despite high childhood immunization coverage, sporadic cases of diphtheria have been reported in Malaysia in recent years. This study aims to evaluate the seroprevalence of diphtheria among the Malaysian population.
Ahmad Faudzi Yusoff, Zatil Zahidah Mohd Sharani, Chee Cheong Kee, Nuur Hafizah Md Iderus, Ahmed Syahmi Syafiq Md Zamri, Tharmarajah Nagalingam, Mohd Safrin Mohamad Bashaabidin, Wan Abdul Hannan Wan Ibadullah, Sumarni Mohd Ghazali, Ainur Yusniza Yusof, Yee Ming Ching, Nurhanani Mohamed Nor, Balqis Kamarudin, Norazah Ahmad, Masita Arip   +14 more
doaj   +2 more sources

Tetanus and Diphtheria Toxoid-Containing Vaccine in Multiple Sclerosis Patients: A Real-World Prospective, Open-Label, Multi-Centre Study [PDF]

Vaccines
Objective: To assess changes in disease activity in Multiple Sclerosis (MS) patients on various disease-modifying-drugs, as well as immunogenicity, safety and clinical tolerability following combined tetanus- and diphtheria-vaccination.
Alexander Winkelmann, Emil C. Reisinger, Katharina Boden, Christoph Metze, Uwe K. Zettl, Micha Loebermann   +5 more
doaj   +2 more sources

A Case of <i>Corynebacterium diphtheriae</i> Native Mitral and Tricuspid Valve Infective Endocarditis Complicated by Shower Emboli. [PDF]

Case Rep Cardiol
Infective endocarditis is a rare phenomenon that may have devastating consequences. While uncommon, the spectrum of causative organisms can include Corynebacterium species. Corynebacterium diphtheriae endocarditis bears a high potential for systemic complications and overall mortality. We present a case of mitral and tricuspid native valve endocarditis
Mashayekan S, Chow T, Gupta J, Huang G.
europepmc   +2 more sources

THE PURIFICATION AND CONCENTRATION OF DIPHTHERIA TOXOID [PDF]

Journal of Experimental Medicine, 1932
By precipitation with acetone at 4°C. a refined diphtheria toxoid was obtained as a dry powder, readily soluble in aqueous solutions. The powder itself appears to be stable. When dissolved in half the original volume of physiological salt solution, the toxoid remained stable, in the cold room, for a period of 7 months. Only toxoids should be used which
A, Wadsworth, J J, Quigley, G R, Sickles
openaire   +2 more sources

METHODS OF CONTROL DIPHTHERIA VACCINE SAFETY [PDF]

Annals of Mechnikov's Institute, 2016
Vaccination success depends not only on the timely coverage of threatened contingents, but also on the quality of vaccines. Every day, the requirements for security guarantees vaccines and their use guarantees of security increases.
Isayenko Ye. Yu, Babych Ye. M, Yelyseyeva I. V, Zhdamarova L. A, Belozersky V. I., Kolpak S. A   +5 more
doaj   +1 more source

Involvement of Mhc Loci in immune responses that are not Ir-gene-controlled [PDF]

, 1982
Twenty-nine randomly chosen, soluble antigens, many of them highly complex, were used to immunize mice of two strains, C3H and B10.RIII. Lymphnode cells from the immunized mice were restimulated in vitro with the priming antigens and the proliferative ...
C. J. Kreo, C. N. Baxevanis, C. N. Baxevanis, D. L. Longo, E. A. Lerner, E. M. Shevach, G. Corradin, H. Lemke, H. O. McDevitt, H. O. McDevitt, J. Sprent, J. T. Nepom, Jan Klein, K. Ozato, L.P. Ryder, M. Shigeta, Matko Marušić, N. Ishii, P. C. Dubriel, P. P. Jones, R. H. Schwartz, R. M. Zinkernagel, U. K. Laemmli, U. Koszinowski, Ulrich Koszinowski, V. T. Oi, Y. Hosaka, Z. A. Nagy, Zoltan A. Nagy   +28 more
core   +1 more source

A Vaccine Against Group B Streptococcus: Recent Advances [PDF]

, 2020
Group B streptococcus (GBS) causes a high burden of neonatal and infant disease globally. Implementing a vaccine for pregnant women is a promising strategy to prevent neonatal and infant GBS disease and has been identified as a priority by the World ...
Carreras-Abad, C, Heath, PT, Le Doare, K, Ramkhelawon, L   +3 more
core   +2 more sources

Nonspecific Regulation of the Number of Immunocompetent Cells Under the Influence of DT Toxoid in Children With Glomerulonephritis

Frontiers in Immunology, 2021
BackgroundStudies aimed at identifying the mechanisms of the immunoregulatory effect of vaccination with diphtheria and tetanus toxoid on the parameters of adaptive immunity in children with kidney pathology are limited.
Mikhail Petrovich Kostinov, Mikhail Petrovich Kostinov, Nelli Kimovna Akhmatova, Olga Olegovna Magarshak, Anna Egorovna Vlasenko, Valentina Borisovna Polishchuk, Aristitsa Mikhailovna Kostinova, Kirill Vadimovich Mashilov   +7 more
doaj   +1 more source