Results 21 to 30 of about 9,669 (183)

Postbooster Antibodies from Humans as Source of Diphtheria Antitoxin

Emerging Infectious Diseases, 2016
Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might
Jesús F. Bermejo-Martin, Ana Avila-Alonso, Milagros González-Rivera, Eduardo Tamayo, Jose María Eiros, Raquel Almansa   +5 more
doaj   +1 more source

Evaluation of Potency on Diphtheria and Tetanus Toxoid for Adult Vaccines by In Vivo Toxin Neutralization Assay Using National Reference Standards [PDF]

Osong Public Health and Research Perspectives, 2018
Objectives Vaccinations against diphtheria and tetanus are essential in providing immunity against these bacterial infections. The potency of diphtheria and tetanus toxoid vaccines can be measured using the in vivo toxin neutralization assay.
Chan Woong Choi, Jae Hoon Moon, Jae Ok Kim, Si Hyung Yoo, Hyeon Guk Kim, Jung-Hwan Kim, Tae Jun Park, Sung Soon Kim   +7 more
doaj   +1 more source

Seroprevalence of an antibody against diphtheria, tetanus, and pertussis among the elderly in Khon Kaen, Thailand

Journal of Health, Population and Nutrition, 2019
Background Owing to a declining birth rate and longer lifespan, the number of elderly people (≥ 60 years) in Thailand has grown rapidly. However, the elderly are at significant risk of infectious diseases because they have never been immunized, because ...
Teeraporn Chinchai, Nawarat Posuwan, Viboonsak Vuthitanachot, Nasamon Wanlapakorn, Yong Poovorawan   +4 more
doaj   +1 more source

Advantages of Toxoid in Diphtheria Prophylaxis [PDF]

American Journal of Public Health and the Nations Health, 1932
ACTIVE immunization against diphtheria has developed during the past 15 years, particularly in North America, into one of the most important specific measures for the prevention of disease. Prior to the use of toxin-antitoxin mixture, smallpox vaccination was considered the most successful individual specific procedure in preventive medicine; but ...
openaire   +2 more sources

Age-Related Dynamics in Post-Vaccine Antibody Immune Response to Diphtheria and Tetanus Toxoid in Bulgarian Subjects

Acta Medica Bulgarica, 2021
In this study, we investigated the age-related dynamics in post-vaccine humoral immunity to diphtheria (DT) and tetanus (TT) toxoids in the Bulgarian population.
Lesichkova S., Mihailova S., Mihaylova A., Gesheva N., Yankova P., Naumova E.   +5 more
doaj   +1 more source

Safety and immunogenicity of an indigenously developed tetanus toxoid, diphtheria toxoid, and acellular pertussis vaccine (Tdap) in adults, adolescents, and children in India

Expert Review of Vaccines, 2023
Background This study assessed safety and immunogenicity of Serum Institute of India Pvt Ltd (SIIPL)’s tetanus toxoid (TT), diphtheria toxoid (DT), and acellular pertussis booster vaccine (Tdap).
Hitt J Sharma, Sameer Parekh, Pramod Pujari, Sunil Shewale, Shivani Desai, Anand Kawade, Mandyam Ravi, Jitendra Oswal, Saji James, N. Mahantashetti, Renuka Munshi, Apurba Ghosh, Venkateshwar Rao, Sundaram Balsubramaniam, P. Varughese, A. Somshekhar, Amy Sarah Ginsburg, Harish Rao, Manish Gautam, Sunil Gairola, Umesh Shaligram   +20 more
doaj   +1 more source

Clinical Characteristics of Corynebacterium ulcerans Infection, Japan

Emerging Infectious Diseases, 2023
Corynebacterium ulcerans is a closely related bacterium to the diphtheria bacterium C. diphtheriae, and some C. ulcerans strains produce toxins that are similar to diphtheria toxin. C.
Akihiko Yamamoto, Toru Hifumi, Manabu Ato, Masaaki Iwaki, Mitsutoshi Senoh, Akio Hatanaka, Shinichi Nureki, Yoshihiro Noguchi, Tomoko Hirose, Yukihiro Yoshimura, Takaaki Urakawa, Shiro Hori, Hiroto Nakada, Tomomasa Terada, Tomoko Ishifuji, Hisayo Matsuyama, Takahiro Kinebuchi, Atsuhito Fukushima, Koji Wake, Ken Otsuji, Takeru Endo, Hirokazu Toyoshima, Ikkoh Yasuda, Takeshi Tanaka, Naoki Takahashi, Kensaku Okada, Toshimasa Hayashi, Taizo Kusano, Minami Koriyama, Norio Otani, Motohide Takahashi   +30 more
doaj   +1 more source

Diphtheria Carriage

Эпидемиология и вакцинопрофилактика, 2018
The diphtheria carriage is a asympthomatic colonization of oro- and nasopharynx by toxigenic and nontoxigenic Corynebacterium diphtheriae. The carriage of toxigenic strains prevents a complete eradication of diphtheria infection in spite of mass toxoid ...
N. N. Kostyukova, V. A. Bechalo
doaj   +1 more source

Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides

Angewandte Chemie International Edition, EarlyView.
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok, Keshav Kishor, Mehman I. Bunyatov, Gerlof P. Bosman, Geert‐Jan Boons   +4 more
wiley   +1 more source

The evaluation of anti-diphtheria toxoid antibodies after 5 years with the primary Tetanus-Diphtheria vaccine in persons aged 6-25 years in Kon Tum, Vietnam: a follow-up study

Journal of Infection in Developing Countries
Introduction: Diphtheria is a serious infectious disease although being vaccine-preventable. 5-year follow-up study aimed to evaluate the persistence of IgG antibodies to diphtheria toxoid after Tetanus-diphtheria primary immunization for persons aged 6-
Tuan Van Le, Van Thi Tuyet Nguyen, Quan Hoang Nguyen, Huong Le Thien Tran, Son Dinh Tran, Chien Chinh Vien   +5 more
doaj   +1 more source