Results 21 to 30 of about 10,764 (219)

METHODS OF CONTROL DIPHTHERIA VACCINE SAFETY [PDF]

Annals of Mechnikov's Institute, 2016
Vaccination success depends not only on the timely coverage of threatened contingents, but also on the quality of vaccines. Every day, the requirements for security guarantees vaccines and their use guarantees of security increases.
Isayenko Ye. Yu, Babych Ye. M, Yelyseyeva I. V, Zhdamarova L. A, Belozersky V. I., Kolpak S. A   +5 more
doaj   +1 more source

Antigen depot is not required for alum adjuvanticity [PDF]

, 2011
Alum adjuvants have been in continuous clinical use for more than 80 yr. While the prevailing theory has been that depot formation and the associated slow release of antigen and/or inflammation are responsible for alum enhancement of antigen presentation
Benson, R.A., Hutchison, S., Gibson, V.B., Vivienne B. Gibson, Garside, P., Sharon Hutchison, Paul Garside, James M. Brewer, Robert A. Benson, Brewer, J.M., Pollock, A.H., Abigail H. Pollock   +11 more
core   +1 more source

Decline of serologic immunity to diphtheria, tetanus and pertussis with age suggested a full life vaccination in mainland China

Human Vaccines & Immunotherapeutics, 2021
Background: Diphtheria-tetanus-pertussis (DTP) vaccine has already been involved in national vaccination program for several decades in China. The immunity against these diseases in the people of all ages is not well investigated.
Dandan Liu, Xiaoping Cheng, Shi Wei, Lin Yuan, Changhui Chen, Kaihu Yao   +5 more
doaj   +1 more source

Nonspecific Regulation of the Number of Immunocompetent Cells Under the Influence of DT Toxoid in Children With Glomerulonephritis

Frontiers in Immunology, 2021
BackgroundStudies aimed at identifying the mechanisms of the immunoregulatory effect of vaccination with diphtheria and tetanus toxoid on the parameters of adaptive immunity in children with kidney pathology are limited.
Mikhail Petrovich Kostinov, Mikhail Petrovich Kostinov, Nelli Kimovna Akhmatova, Olga Olegovna Magarshak, Anna Egorovna Vlasenko, Valentina Borisovna Polishchuk, Aristitsa Mikhailovna Kostinova, Kirill Vadimovich Mashilov   +7 more
doaj   +1 more source

Reduced antibody responses to vaccinations in children exposed to polychlorinated biphenyls. [PDF]

PLoS Medicine, 2006
Developmental exposure to polychlorinated biphenyls (PCBs) has been implicated as a possible cause of deficient immune function in children. This study was designed to assess whether prenatal and postnatal exposure to PCBs impacts on antibody response to
Carsten Heilmann, Philippe Grandjean, Pál Weihe, Flemming Nielsen, Esben Budtz-Jørgensen   +4 more
doaj   +1 more source

A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate [PDF]

, 2016
Three important physical properties which may affect the performance of glycoconjugate vaccines against serious disease are molar mass (molecular weight), heterogeneity (polydispersity), and conformational flexibility in solution.
Harding, Stephen E., Conrath, K., Almuntari, F., Almutairi, Fahad M., Duvivier, Pierre, Harding, S. E., Adams, G. G., Morris, Gordon, Duvivier, P., Morris, Gordon A., Abdelhameed, Ali Saber, Adams, Gary G., Abdelhameed, A. S., Conrath, Karel, GSK Vaccines, Rue de l’Institut 89, B-1330 Rixensart, Belgium   +14 more
core   +1 more source

Effect of HIV exposure and timing of antiretroviral therapy initiation on immune memory responses to diphtheria, tetanus, whole cell pertussis and hepatitis B vaccines

Expert Review of Vaccines, 2019
Objectives: We evaluated memory responses and antibody persistence to diphtheria-toxoid, tetanus-toxoid, whole-cell-pertussis (DTwP), and Hepatitis-B vaccines in HIV-unexposed, HIV-exposed-uninfected and HIV-infected children previously randomized to ...
Omphile E. Simani, Alane Izu, Marta C. Nunes, Avy Violari, Mark F. Cotton, Nadia Van Niekerk, Peter V. Adrian, Shabir A. Madhi   +7 more
doaj   +1 more source

Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans

Emerging Infectious Diseases, 2019
Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans.
Ken Otsuji, Kazumasa Fukuda, Midori Ogawa, Mitsumasa Saito   +3 more
doaj   +1 more source

Postbooster Antibodies from Humans as Source of Diphtheria Antitoxin

Emerging Infectious Diseases, 2016
Diphtheria antitoxin for therapeutic use is in limited supply. A potential source might be affinity-purified antibodies originally derived from plasma of adults who received a booster dose of a vaccine containing diphtheria toxoid. These antibodies might
Jesús F. Bermejo-Martin, Ana Avila-Alonso, Milagros González-Rivera, Eduardo Tamayo, Jose María Eiros, Raquel Almansa   +5 more
doaj   +1 more source

Evaluation of Potency on Diphtheria and Tetanus Toxoid for Adult Vaccines by In Vivo Toxin Neutralization Assay Using National Reference Standards [PDF]

Osong Public Health and Research Perspectives, 2018
Objectives Vaccinations against diphtheria and tetanus are essential in providing immunity against these bacterial infections. The potency of diphtheria and tetanus toxoid vaccines can be measured using the in vivo toxin neutralization assay.
Chan Woong Choi, Jae Hoon Moon, Jae Ok Kim, Si Hyung Yoo, Hyeon Guk Kim, Jung-Hwan Kim, Tae Jun Park, Sung Soon Kim   +7 more
doaj   +1 more source