Results 51 to 60 of about 9,669 (183)

Conformational changes in diphtheria toxoids [PDF]

open access: yesFEBS Letters, 1987
Monoclonal antibodies (Mab) were raised against CRM197, a non‐toxic mutant of diphtheria toxin (DT). The ability of four Mabs to bind DT and the six functional mutants CRM197, CRM176, CRM228, CRM1001, CRM45 and CRM30 was assessed by immunoblotting and by a radioimmunoassay in which the protein antigen in solution competes with labeled CRM197 for the ...
Bigio, Massimo   +5 more
openaire   +2 more sources

The Cinderella tree, Quillaja saponaria – A soap story

open access: yesPLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 439-451, March 2026.
Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley   +1 more source

Safety and Immunogenicity of Two Doses of Quadrivalent Meningococcal Conjugate Vaccine or One Dose of Meningococcal Group C Conjugate Vaccine, both Administered Concomitantly with Routine Immunization to 12- to 18-Month-Old Children

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2014
OBJECTIVES:To describe the immunogenicity and safety of a two-dose series of a quadrivalent meningococcal (serogroups A, C, Y and W) polysaccharide diphtheria toxoid conjugate vaccine (MenACYW-D) administered to toddlers.
Francisco Noya   +4 more
doaj   +1 more source

IMMUNIZATION WITH DIPHTHERIA TOXOID (ANATOXINE RAMON)

open access: yesAmerican Journal of Public Health, 1927
THE work reported in this paper has to do with two problems: namely, the dosage of diphtheria toxoid and the value of the Schick test in studies of active immunity against diphtheria. The dosage consisted of two injections of toxoid given subcutaneously with an interval of a month between injections.* The work of immunization was carried out on a group
P J, Moloney, C J, Fraser
openaire   +3 more sources

Perspectives on Pertussis Prevention

open access: yes
Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Diphtheria outbreak in Jakarta and Tangerang, Indonesia: Epidemiological and clinical predictor factors for death.

open access: yesPLoS ONE, 2021
BackgroundIn 2017, a diphtheria outbreak occurred in several provinces in Indonesia. The aim of this study was to identify predictors of mortality outcome of pediatric patients with clinical diphtheria.MethodsA retrospective cohort study was conducted ...
Eggi Arguni   +3 more
doaj   +1 more source

A Case of Corynebacterium diphtheriae Native Mitral and Tricuspid Valve Infective Endocarditis Complicated by Shower Emboli

open access: yesCase Reports in Cardiology, Volume 2026, Issue 1, 2026.
Infective endocarditis is a rare phenomenon that may have devastating consequences. While uncommon, the spectrum of causative organisms can include Corynebacterium species. Corynebacterium diphtheriae endocarditis bears a high potential for systemic complications and overall mortality. We present a case of mitral and tricuspid native valve endocarditis
Sara Mashayekan   +4 more
wiley   +1 more source

Pilot Study to Improve In Vitro Identification of Culprit Drugs in SJS/TEN Using Granzyme B and Granulysin Secretion Assays

open access: yesJournal of Immunology Research, Volume 2026, Issue 1, 2026.
Introduction Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) are severe cutaneous adverse drug reactions (SCARs) with high morbidity and mortality. Accurate identification of the culprit drug is critical and remains challenging, whereas current in vitro tests such as lymphocyte transformation test (LTT) have limited sensitivity.
Yuttana Srinoulprasert   +6 more
wiley   +1 more source

Occupational Health: Analysis of the Psychological Impact of Exposure to Needlestick and Sharps Injuries Among Primary Health Care Professionals

open access: yesNursing Research and Practice, Volume 2026, Issue 1, 2026.
Occupational exposure to biological material, particularly needlestick and sharps injuries, is a relevant public health concern in Primary Health Care (PHC), as it combines infectious risk with psychological sequelae that are often underestimated. This study aimed to analyze the occurrence of needlestick and sharps injuries and their psychological ...
Talita Priscilla da Silva Guerra   +6 more
wiley   +1 more source

An Atypical Complex Regional Pain Syndrome Type 1 Following Diphtheria-Tetanus Vaccination

open access: yesMedicine Science, 2016
A 20-year-old male patient was admitted to Infectious diseases outpatient clinic with 25 days’ history of pain and swelling of the left hand and forearm.
Ergenekon Karagoz   +5 more
doaj   +1 more source

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