Results 61 to 70 of about 79,524 (248)

Trained Immunity in Childhood Vaccination

Acta Paediatrica, Volume 115, Issue 11, Page 2402-2413, November 2026.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai, Lubnaa Hossenbaccus, Eva Kaufmann   +2 more
wiley   +1 more source

Immunogenicity, safety, and reactogenicity of combined reduced-antigen-content diphtheria-tetanus-acellular pertussis vaccine administered as a booster vaccine dose in healthy Russian participants: a phase III, open-label study

Human Vaccines & Immunotherapeutics, 2021
As vaccine-induced immunity and protection following natural pertussis infection wane over time, adults and adolescents may develop pertussis and become transmitters to unprotected infants.
Asmik Asatryan, Nadia Meyer, Michael Scherbakov, Victor Romanenko, Irina Osipova, Anna Galustyan, Olga Shamsheva, Tatiana Latysheva, Tatyana Myasnikova, Nathalie Baudson, Monique Dodet, Stebin Xavier, Lauriane Harrington, Anastasia Kuznetsova, Laura Campora, Peter Van den Steen   +15 more
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Additional file 1 of Seroprevalence of IgG antibodies against diphtheria antitoxin among migrant workers in Singapore, 2016–2019

, 2022
Additional file 1: Supplementary Table 1. Seroprevalence of IgG antibodies against diphtheria antitoxin in Bangladesh, China, Indonesia and Malaysia. Supplementary Table 2.
Matthias Paul Han Sim Toh (10220975), Aysha Farwin (11605137), Irving Charles Boudville (6703700), Vernon Jian Ming Lee (6656754), Qi Gao (133189), Raymond Tzer-Pin Lin (10220978), Li Wei Ang (6656751), Mark I-Cheng Chen (7384223), Angela Chow (245482), Yee Sin Leo (8879534), Lin Cui (163750)   +10 more
core   +1 more source

Effect of Ibrutinib on Hmphocytic Leukemia: a Single-Center Experience

Hematology/Oncology and Stem Cell Therapy, 2022
Objective/Background: In the era of novel agents, Bruton tyrosine kinase (BTK) inhibitors have changed the dynamics of treating chronic lymphocytic leukemia. However, small studies have shown conflicting results regarding the additive humoral dysfunction
Hamza Hassan, Mohammad Ammad Ud Din, Saad Jamshed, Jonathan Bress, S Shahzad Mustafa   +4 more
doaj   +1 more source

PURIFICATION OF DIPHTHERIA TOXOID BY CONTINUOUS ELECTROPHORESIS ON FILTER PAPER

, 1953
A separation of purified diphtheria toxoid in a continuous electrophoresis apparatus has been achieved and resulting components have been.collected in quantities sufficient for testing and elaboration. The simple and inexpensive apparatus constructed of
M. D. Poulik
core   +1 more source

Methods of control diphtheria vaccine safety

Annals of Mechnikov's Institute, 2020
Vaccination success depends not only on the timely coverage of threatened contingents, but also on the quality of vaccines. Every day, the requirements for security guarantees vaccines and their use guarantees of security increases.
Ye Isayenko, Ye Babych, I Yelyseyeva, L Zhdamarova, V Belozersky, S Kolpak   +5 more
doaj  

Reduced Expression of Magnesium Transport Proteins in the Distal Convoluted Tubule of Clcnkb‐Deficient Mice May Explain Urinary Magnesium Wasting in Classical Bartter Syndrome

Acta Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT Aim The kidney thick ascending limb (TAL) plays a key role in the transport of sodium, chloride, potassium, calcium, and magnesium. Bartter syndrome is a hypokalemic, salt‐losing tubulopathy caused by impaired TAL function. Pathogenic variants in SLC12A1 or KCNJ1 cause antenatal Bartter syndrome, and variants in CLCNKB result in classical ...
Marleen L. A. Kortenoeven, Milos Bogdanovic, Ida Appel, Karsten Skjødt, Ernst‐Martin Fuchtbauer, Kirsten Madsen, Lars Lund, Régine Chambrey, Dominique Eladari, R. Todd Alexander, Christian A. Hübner, J. Christopher Hennings, Henrik Dimke   +12 more
wiley   +1 more source

Identification of Formaldehyde-Induced Modifications in Diphtheria Toxin [PDF]

, 2019
Diphtheria toxoid is produced by detoxification of diphtheria toxin with formaldehyde. This study was performed to elucidate the chemical nature and location of formaldehyde-induced modifications in diphtheria toxoid.
Uittenbogaard, J., Metz, B., Jiskoot, W., Danial, M., Tilstra, W., Crommelin, D.J.A., Michiels, T., Meiring, H.D., Hennink, W.E., Kersten, G.F.A.   +9 more
core   +1 more source

Determination of DTaP vaccine potency by multiplex immunogenicity testing using electrochemiluminescence

npj Vaccines
Lot release testing of diphtheria, tetanus and acellular pertussis vaccines traditionally relied on in vivo protection models involving challenge of laboratory animals with toxins.
Bärbel Friedrichs, Simone Rehg, Kay-Martin Hanschmann, Volker Öppling, Isabelle Bekeredjian-Ding   +4 more
doaj   +1 more source