Results 61 to 70 of about 17,354 (224)
Mixing is required for uniform reconstitution of filter-dried protein antigens in a single-injection vaccine formulation [PDF]
, 2018 Ambient temperature filter dried vaccine formulations have been proposed to simultaneously achieve thermostability and offer a ready-to-use immunisation device that combines reconstitution and injection.
Edwards, Alexander D. +1 more
core +1 more source
Journal of Extracellular Vesicles, Volume 14, Issue 9, September 2025.ABSTRACT Outer membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development. OMVs possess inherent immunostimulatory properties due to the presence of pathogen‐associated molecular patterns (PAMPs), providing self‐adjuvanting capabilities and the ability to ...
Asja Garling +4 more
wiley +1 more source
npj VaccinesLot release testing of diphtheria, tetanus and acellular pertussis vaccines traditionally relied on in vivo protection models involving challenge of laboratory animals with toxins.
Bärbel Friedrichs +4 more
doaj +1 more source
Педиатрическая фармакология, 2020 The increase in the incidence of vaccine-preventable infections is due to the low level of immunological protection of the population, which against the background of active migration processes can determine high risks of outbreaks of infectious diseases
Diana V. Sutovskaya +4 more
doaj +1 more source
DETERMINATION OF REGIMES FOR DIPHTHERIA EXOTOXIN MODIFICATION BY CHEMICAL AND PHYSICOCHEMICAL METHODS [PDF]
Annals of Mechnikov's Institute, 2011 The possibility of diphtheria toxoid obtaining using chemical (amino sugars, organic acids) and physicochemical (amino sugars, organic acids, ultrasound, temperature) factors was studied.
Antusheva T.I. +7 more
doaj
Canadian Journal of Infectious Diseases and Medical Microbiology, 2014 OBJECTIVES:To describe the immunogenicity and safety of a two-dose series of a quadrivalent meningococcal (serogroups A, C, Y and W) polysaccharide diphtheria toxoid conjugate vaccine (MenACYW-D) administered to toddlers.
Francisco Noya +4 more
doaj +1 more source
PLoS ONE, 2021 BackgroundIn 2017, a diphtheria outbreak occurred in several provinces in Indonesia. The aim of this study was to identify predictors of mortality outcome of pediatric patients with clinical diphtheria.MethodsA retrospective cohort study was conducted ...
Eggi Arguni +3 more
doaj +1 more source
Differential activation of CD57-defined natural killer cell subsets during recall responses to vaccine antigens [PDF]
, 2013 Natural killer (NK) cells contribute to the effector phase of vaccine-induced adaptive immune responses, secreting cytokines and releasing cytotoxic granules.
Goodier, Martin R. +4 more
core +2 more sources
IMMUNIZATION WITH DIPHTHERIA TOXOID (ANATOXINE RAMON)
American Journal of Public Health, 1927 THE work reported in this paper has to do with two problems: namely, the dosage of diphtheria toxoid and the value of the Schick test in studies of active immunity against diphtheria. The dosage consisted of two injections of toxoid given subcutaneously with an interval of a month between injections.* The work of immunization was carried out on a group
P J, Moloney, C J, Fraser
openaire +3 more sources
Clinical progress note: Pertussis
Journal of Hospital Medicine, Volume 20, Issue 8, Page 862-865, August 2025.Visual Abstract Abstract Pertussis, commonly known as whooping cough, is a vaccine‐preventable respiratory disease with rising incidence due to declining vaccination rates and waning immunity. The most severe disease course is seen in unvaccinated or incompletely vaccinated infants less than 2 months of age, accounting for the largest burden of ...
Samantha Hanna, Nicole Samies
wiley +1 more source