Results 81 to 90 of about 17,354 (224)

Alzheimer's Disease and Frontotemporal Dementia: A Review of Pathophysiology and Therapeutic Approaches

open access: yesJournal of Neuroscience Research, Volume 103, Issue 5, May 2025.
ABSTRACT Alzheimer's disease (AD) is a devastating form of dementia, with the number of affected individuals rising sharply. The main hallmarks of the disease include amyloid‐beta plaque deposits and neurofibrillary tangles consisting of hyperphosphorylated tau protein, besides other pathological features that contribute to the disease's complexity ...
Sally Kelliny   +2 more
wiley   +1 more source

A State‐of‐the‐Art Appraisal of Nanomaterials in Microneedles in the Delivery of Therapeutics and Vaccines

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 3, March 2025.
Nanomaterial‐integrated microneedles revolutionize transdermal delivery, enabling targeted and controlled administration of therapeutics and vaccines. This review explores advancements in design, manufacturing, and applications, emphasizing enhanced drug stability, bioavailability, and patient adherence. Key preclinical and clinical findings as well as
Bwalya Angel Witika   +3 more
wiley   +1 more source

Penggunaan Mencit untuk Pemeriksaan Potensi Toksoid Difteri [PDF]

open access: yes, 1987
At present, the potency test of diphtheria toxoid is carried out on Guinea pigs as experimental animals. Production of a large number of Guinea pigs suitable for experiment is still, considered to be a substantial problem, especially in some developing ...
Isbagio, D. W. (Dyah)   +3 more
core  

The role of the gut microbiota in regulating responses to vaccination: current knowledge and future directions

open access: yesThe FEBS Journal, Volume 292, Issue 6, Page 1480-1499, March 2025.
Vaccination plays a crucial role in mediating protection against infectious diseases, but immune responses to vaccination are highly variable and frequently sub‐optimal in vulnerable populations. Here, we review the latest preclinical and clinical evidence demonstrating that the gut microbiota plays a significant role in regulating immune responses to ...
Charné Rossouw   +2 more
wiley   +1 more source

The Effect of Maternal Tetanus Immunization on Children’s Schooling Attainment in Matlab, Bangladesh: Follow-up of a Randomized Trial [PDF]

open access: yes
We investigate the effects of ante-natal maternal vaccination against tetanus on the schooling attained by children in Bangladesh. Maternal vaccination prevents the child from acquiring tetanus at birth through blood infection and substantially reduces ...
Abdur Razzaque   +5 more
core  

Rare human skin infection with Corynebacterium ulcerans: transmission by a domestic cat [PDF]

open access: yes, 2018
Corynebacterium ulcerans is mainly known for its ability to cause animal infections. Some strains of C. ulcerans produce diphtheria toxin, which can cause life-threatening cardiopathies and neuropathies in humans. Human cutaneous C. ulcerans infection is
Bloemberg, G.   +6 more
core  

Novel Corynebacterium diphtheriae in domestic cats [PDF]

open access: yes, 2010
Novel nontoxigenic Corynebacterium diphtheriae was isolated from a domestic cat with severe otitis. Contact investigation and carrier study of human and animal contacts yielded 3 additional, identical isolates from cats, although no evidence of zoonotic ...
Hall, Aron J.   +14 more
core   +1 more source

Pertussis Vaccination in Pregnant Women at the EMMC Family Medicine Center [PDF]

open access: yes, 2016
Pertussis, also known as whooping cough, primarily affects infants less than 12 months of age and frequently requires lengthy hospital stays. Maine has the 3rd highest rate of documented pertussis cases in the nation.
Doughty, Elizabeth S
core   +1 more source

Integrated Serologic Surveillance of Population Immunity and Disease Transmission. [PDF]

open access: yes, 2018
Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus,
Arnold, Benjamin F   +3 more
core   +1 more source

Is Diphtheria Booster Vaccination Still Necessary in Turkey?

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2018
Introduction: Diphtheria is a serious disease that can be prevented by vaccination. The aim of the study was to determine immunity against diphtheria and the necessity of booster doses in the adult population.Materials and Methods: Serum antibody levels ...
Sule Eren CAKAR   +5 more
doaj   +1 more source

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