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Diquat intoxication

Annals of Emergency Medicine, 1983
Reported is the case of a 23-year-old man who ingested 300 mL of Reglone. He developed vomiting five to 10 minutes after ingestion. Shortly thereafter, he developed renal and central nervous system manifestations of toxicity, followed by cardiovascular collapse and death 14 hours after admission.
L G, McCarthy, C P, Speth
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Diquat cataract in the rat

Experimental Eye Research, 1970
We have confirmed that lens opacities develop in rats that are fed a diet containing 0·05–0·075% of diquat (1,1′-ethylene-2,2′-dipyridylium dibromide). The pathological changes in the lens are described. Radioactivity appears in the lens and other ocular tissues after intraperitoneal injection of [14C]diquat.
A, Pirie, J R, Rees
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Mutagenic and embryotoxic effects of paraquat and diquat [PDF]

open access: possibleBulletin of Environmental Contamination and Toxicology, 1980
In our previous report on the in vivo cytogenic effect of paraquat, it was concluded that the compound had no mutagenic effect on the bone marrow cells of the mouse (SELYPES et al. 1978). In the first part of this study we investigated whether dlquat would have a mutagenic effect under similar experimental circumstances, and in the second part, we ...
Selypes A.   +2 more
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Resolution of the First Nonracemic Diquats

Chemistry – A European Journal, 2010
AbstractThree tricyclic diquats with an eight‐membered ring were prepared and shown to be the first configurationally stable derivatives of their kind. Resolution was achieved by using chiral hexacoordinated phosphorus BINPHAT and TRISPHAT anions. The diquat cations were obtained in high diastereo‐ and enantiomeric purity (ee>96 % in most cases).
Vachon, Jérôme   +2 more
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Isolation of Diquat with SepPak C18

Journal of Analytical Toxicology, 1989
The herbicide paraquat (1,1 '-dimethyl-4,4 '-bipyridylium dichloride) has been isolated from plasma and serum without deproteinization by SepPak C,~ (1). Last year, its concentration in a commercial preparation in Japan was reduced to one fifth, from 24~ to 5~ (as its ion), due to its high mortality rate. To compensate, another herbicide, diquat (1,1 '-
H, Maruyama, M, Ide
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Pseudocryptand Hosts for Paraquats and Diquats

The Journal of Organic Chemistry, 2018
H-bonding interaction of acidic moieties (CH2OH, COOH) at the 5- and 5'-positions of bis(1,3-phenylene)-32-crown-10 (1) with di- or tritopic anions leads to enhanced formation of inclusion complexes with N,N'-dialkyl-4,4'-bipyridinium salts ("paraquats", 2); the enforced folding of the crown ethers into pseudocryptands thus leads to pseudo ...
Jason W. Jones   +6 more
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Worker exposure to paraquat and diquat

Archives of Environmental Contamination and Toxicology, 1983
Exposure of workers applying paraquat to fields of tomatoes and citrus, and diquat to waterways containing water hyacinths and hydrilla, was monitored with dermal α-cellulose pads attached at each of ten body locations and with personal air monitors.
G A, Wojeck   +3 more
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Vaginally Applied Diquat Intoxication

Journal of Toxicology: Clinical Toxicology, 1999
We report the case of a woman who introduced 20 mL of diquat concentrate intravaginally. Abdominal pain, vomiting, diarrhea, burning chest pains, and somnolence appeared within the first 24 hours. The vulva and vagina were corrosively inflamed. Acute renal failure appeared on the third day and was treated by 6 hemodialyses over 6 days.
Rudež, Josip   +2 more
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