Results 201 to 210 of about 29,806 (309)

Prioritizing Feasible and Impactful Actions to Enable Secure AI Development and Use in Biology

Biotechnology and Bioengineering, EarlyView.
ABSTRACT As artificial intelligence continues to enhance biological innovation, the potential for misuse must be addressed to fully unlock the potential societal benefits. While significant work has been done to evaluate general‐purpose AI and specialized biological design tools (BDTs) for biothreat creation risks, actionable steps to mitigate the risk
Josh Dettman, Emily Lathrop, Aurelia Attal‐Juncqua, Matthew Nicotra, Allison Berke   +4 more
wiley   +1 more source

Impact of Direct-Acting Antivirals on Extrahepatic Manifestations in Chronic Hepatitis C: A Narrative Review with a Hermeneutic Approach. [PDF]

Healthcare (Basel)
Balta AAS, Ignat MD, Barbu RE, Dumitru C, Radaschin DS, Bulza V, Mateescu Costin SA, Pleșea-Condratovici C, Baroiu L.   +8 more
europepmc   +1 more source

HCV avidity as a tool for detection of recent HCV infection: sensitivity depends on HCV genotype [PDF]

, 2018
Araujo, Barreiro, Coppola, Coppola, Coughlin, Cunningham, Dominguez, Dore, Feld, Gaudy-Graffin, Genders, Giese, Gower, Grebely, Grebely, Grebely, Grebely, Greiner, Gutiérrez, Hajarizadeh, Hajarizadeh, Hajarizadeh, Hauser, Kanno, Kassanjee, Kassanjee, Kassanjee, Klimashevskaya, Mangia, Martin, Netski, Parekh, Patel, Pawlotsky, Pawlotsky, Polanec, Sacks-Davis, Sagnelli, Shepherd, Sulkowski, Thacker, Thomson, Tomkins, Vickerman, Ward, Wiessing   +45 more
core   +1 more source

A Mechanistic Model of rAAV Production in Synthetic Cell Lines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan, Han‐Jung Kuo, Yu‐Chieh Lin, Yen‐An Lu, Wei‐Shou Hu, Qi Zhang   +5 more
wiley   +1 more source

Hepatocellular Carcinoma Recurrence in Patients with Chronic Hepatitis C Infection Treated with Direct-Acting Antivirals: A Systematic Review and Meta-Analysis. [PDF]

Infect Dis Ther
Lindsley K, Burroughs M, Hernandez-Lopez C, Wang Y, Marcinak J, Chiuve SE, Haber BA, Uyei J, Navadeh S, De Marco G, Hill DD.   +10 more
europepmc   +1 more source

Global policy and access to new hepatitis C therapies for people who inject drugs [PDF]

, 2015
Aspinall, Esther, Doyle, Joseph S., Gore, Charles, Hellard, Margaret E., Hutchinson, Sharon, Quinn, Brendan, Wiktor, Stefan   +6 more
core   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Albumin-bilirubin score reflects the extent of liver fibrosis in chronic hepatitis C patients treated with direct-acting antivirals. [PDF]

World J Hepatol
Ewid M, Sherif H, Saquib N, Alammari AM, Ismail AAM, Alkahlot MH, Ahmed ZT, Al-Zabidi FZM, Al Mutiri N.   +8 more
europepmc   +1 more source

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source

Normalization of serum alpha fetoprotein after direct acting antivirals in hepatitis C patients lowers hepatocellular carcinoma risk. [PDF]

Sci Rep
Lin CK, Wang SH, Lee TH.
europepmc   +1 more source