Results 161 to 170 of about 4,963,210 (228)

5-Aryltetrazoles from Direct C–H Arylation with Aryl Bromides

The Journal of Organic Chemistry, 2020
A mild, direct C-H arylation of 1-substituted tetrazoles to 5-aryltetrazoles is developed using a Pd/Cu cocatalytic system with readily available aryl bromides. The methodology avoids late-stage usage of azides and tolerates a wide range of functionalities.
Yuan Zhang, Jack Chang Hung Lee, Matthew R. Reese, Brian P. Boscoe, John M. Humphrey, Christopher J. Helal   +5 more
openaire   +2 more sources

Direct Palladium-Catalyzed Arylation of Cyclopropenes

Journal of the American Chemical Society, 2005
The first examples of direct palladium-catalyzed arylation and heteroarylation of cyclopropenes have been demonstrated. This method allows for efficient synthesis of various tetrasubstituted cyclopropenes, incuding nonracemic cyclopropenes, which are not available via known asymmetric cyclopropenation methods.
Stepan, Chuprakov, Michael, Rubin, Vladimir, Gevorgyan   +2 more
openaire   +2 more sources

Direct Arylation of Benzothiazoles and Benzoxazoles with Aryl Boronic Acids

Chemistry – A European Journal, 2011
Direct arylation of benzothiazole (IV) and benzoxazole (I) with a wide range of arylboronic acids is smoothly achieved in the presence of a Pd—Cu cocatalyst under aerobic conditions.
Ranjit, S., Liu, X.
openaire   +2 more sources

Scope of direct arylation of fluorinated aromatics with aryl sulfonates

Organic & Biomolecular Chemistry, 2012
The scope and limitations of direct arylation of fluorinated aromatics with aryl sulfonates was examined. Pd(OAc)(2), in the presence of MePhos and KOAc in THF, efficiently catalyzed the direct arylation of fluoro aromatics with aryl triflates under ambient conditions. Sterically hindered triflates and heteroaryl triflates gave good to excellent yields
Chang, J.W.W., Chia, E.Y., Chai, C.L.L., Seayad, J.   +3 more
openaire   +2 more sources

Catalytic Direct β-Arylation of Simple Ketones with Aryl Iodides

Journal of the American Chemical Society, 2013
Herein we report a direct β-arylation of simple ketones with widely available aryl iodides, combining palladium-catalyzed ketone oxidation, aryl-halide activation, and conjugate addition through a single catalytic cycle. Simple cyclic ketones with different ring-sizes, as well as acyclic ketones, can be directly arylated at the β-position with complete
Zhongxing, Huang, Guangbin, Dong
openaire   +2 more sources

Para-Selective Arylation of Arenes: A Direct Route to Biaryls by Norbornene Relay Palladation.

Angewandte Chemie, 2020
Biaryls are extremely important structural motifs in natural products, biologically active components and pharmaceuticals. Selective synthesis of biaryls by distinguishing the subtle reactivity difference of distal arene-C-H bonds are significantly ...
U. Dutta, Sandip Porey, Sandeep Pimparkar, Astam Mandal, Jagrit Grover, Adithyaraj Koodan, D. Maiti   +6 more
semanticscholar   +1 more source

Palladium-Catalyzed Direct Arylation of Methyl Sulfoxides with Aryl Halides

Journal of the American Chemical Society, 2013
The palladium-catalyzed α-arylation of unactivated sulfoxides has been developed. The weakly acidic α-protons of sulfoxides are reversibly deprotonated by LiOtBu, and a palladium phosphine complex facilitates the arylation. A variety of aryl methyl sulfoxides were coupled with aryl bromides.
Tiezheng, Jia, Ana, Bellomo, Kawtar E L, Baina, Spencer D, Dreher, Patrick J, Walsh   +4 more
openaire   +2 more sources

Direct C–H Arylation of Aldehydes by Merging Photocatalyzed Hydrogen Atom Transfer with Palladium Catalysis

ACS Catalysis, 2020
Herein, we report that merging palladium catalysis with hydrogen atom transfer (HAT) photocatalysis enabled direct arylations and alkenylations of aldehyde C–H bonds, facilitating visible light-cat...
Lu Wang, Ting Wang, G. Cheng, Xiaobao Li, Jun-jie Wei, Bingyi Guo, Caijuan Zheng, Guangying Chen, Chongzhao Ran, Chao Zheng   +9 more
semanticscholar   +1 more source

Palladium-Catalyzed Direct Arylation of Aryl(azaaryl)methanes with Aryl Halides Providing Triarylmethanes

Organic Letters, 2007
Direct arylation of aryl(azaaryl)methanes with aryl halides takes place at the benzylic position in the presence of a hydroxide base under palladium catalysis to yield triarylmethanes.
Niwa, Takashi, Yorimitsu, Hideki, Oshima, Koichiro   +2 more
openaire   +2 more sources

Iron-Catalyzed Direct Arylation through an Aryl Radical Transfer Pathway

Journal of the American Chemical Society, 2010
A general and efficient iron-catalyzed direct arylation of benzene and hetereoaryl derivatives using a cost-effective and environmentally benign catalyst is described. The reaction is performed under neat conditions and can proceed at room temperature.
Frédéric, Vallée, James J, Mousseau, André B, Charette   +2 more
openaire   +2 more sources