Results 51 to 60 of about 4,963,210 (228)

The Challenging P‐Alkylation of Aromatic Phosphorus Heterocycles and Follow‐Up Reactions

ChemistryEurope, EarlyView.
P‐alkylation of λ3σ2‐phosphinines is hindered by weak nucleophilicity and scarce synthetic access, previously requiring multistep routes or extreme electrophiles. A direct ambient‐condition method is reported using 3,5‐bis(trimethylsilyl)‐phosphinine/B(C6F5)3 with esters or iso(thio)cyanates to generate stable 1‐R‐phosphininium salts.
Samantha Frank, Ádám Horváth, Duy Nguyen, Moritz J. Ernst, Simon Steinhauer, Zoltán Benkő, Christian Müller   +6 more
wiley   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Nucleophilic Arylation of Halopurines Facilitated by Brønsted Acid in Fluoroalcohol

Molecules, 2019
Various aryl-substituted purine derivatives were synthesized through the direct arylation of halopurines with aromatic compounds, facilitated by the combination of triflic acid and fluoroalcohol.
Naoko Takenaga, Toshitaka Shoji, Takayuki Menjo, Akiko Hirai, Shohei Ueda, Kotaro Kikushima, Tomonori Hanasaki, Toshifumi Dohi   +7 more
doaj   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Direct catalytic arylation of heteroarenes with meso-bromophenyl-substituted porphyrins

Beilstein Journal of Organic Chemistry, 2017
The arylation of mono-, di- and tetra-meso-bromophenyl-substituted porphyrins with the heteroarenes containing “acidic” C–H bonds, such as benzoxazole, benzothiazole and N-methylimidazole was studied in the presence of three alternative catalytic systems:
Alexei N. Kiselev, Olga K. Grigorova, Alexei D. Averin, Sergei A. Syrbu, Oskar I. Koifman, Irina P. Beletskaya   +5 more
doaj   +1 more source

Direct Pd‐Catalyzed Arylation of 1,2,3‐Triazoles. [PDF]

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stepan, Chuprakov, Natalia, Chernyak, Alexander S, Dudnik, Vladimir, Gevorgyan   +3 more
openaire   +3 more sources

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

[RuCl3(H2O)n]-catalyzed direct arylations

Tetrahedron, 2008
Abstract Catalytic amounts of economically attractive [RuCl3(H2O)n] allow for direct arylations via C–H bond functionalization with aryl bromides under phosphine ligand-free reaction conditions. Thereby, a variety of functionalized (hetero)aryl bromides, bearing either electron-withdrawing or electron-releasing substituents, can be employed for ...
Ackermann, Lutz, Althammer, Andreas, Born, Robert   +2 more
openaire   +2 more sources

Unprecedented Access to β‐Arylated Selenophenes through Palladium‐Catalysed Direct Arylation [PDF]

Chemistry – A European Journal, 2017
AbstractSeveral reported methods allow access to α‐arylated selenophenes, whereas the synthesis of β‐arylated selenophenes remains very challenging. Here, the Pd‐catalysed coupling of benzenesulfonyl chlorides with selenophenes affording regiospecific β‐arylated selenophenes is reported.
Skhiri, Aymen, Salem, Ridha Ben, Soulé, Jean-François, Doucet, Henri   +3 more
openaire   +3 more sources

Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives

Chemistry – A European Journal, EarlyView.
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome, Péter P. Fehér, András Stirling, Csongor G. Németh, Tamás Hergert, György M. Keserű, Péter Ábrányi‐Balogh   +6 more
wiley   +1 more source