Flow Equations for Free-Flowable Particle Fractions of Sorbitol for Direct Compression: An Exploratory Multiple Regression Analysis of Particle and Orifice Size Influence. [PDF]
Pharmaceutics, 2022 Marushka J +3 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
PharmaceuticalsObjective: This article investigated the structural characteristics, powder properties, and performance variations of co-processed pregelatinized starch (PS) and microcrystalline cellulose (MCC) at varying ratios.
Yong Bi +4 more
doaj +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Evaluation of the application of cashew gum as an excipient to produce tablets
PolímerosCashew gum is extracted from the exudate of the giant cashew tree (Anacardium occidentale L.). The objective of this work was to study the extraction and purification of cashew gum through experiments to characterize its structures and physicochemical ...
Ana Paula de Sá Pinto +2 more
doaj +1 more source
Performance Evaluation of a Novel Biosourced Co-Processed Excipient in Direct Compression and Drug Release. [PDF]
Polymers (Basel), 2021 Benabbas R +5 more
europepmc +1 more source
From direct tagging to Tagging with sentences compression
CoRR, 2018 In essence, the two tagging methods (direct tagging and tagging with sentences compression) are to tag the information we need by using regular expression which basing on the inherent language patterns of the natural language. Though it has many advantages in extracting regular data, Direct tagging is not applicable to some situations.
openaire +2 more sources
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +110 more
wiley +1 more source
Development of Oral Tablet Formulation Containing Erlotinib: Randomly Methylated-β-cyclodextrin Inclusion Complex Using Direct Compression Method [PDF]
Turk J Pharm Sci, 2021 Erdoğar N.
europepmc +1 more source