Results 141 to 150 of about 2,104,910 (277)

An Improved Bio-Orientation Method Based on Direct Sunlight Compensation for Imaging Polarization Sensor

Journal of Imaging
Direct sunlight in complex environmental conditions severely interferes with the light intensity response for imaging Polarization Sensor (PS), leading to a reduction in polarization orientation accuracy.
Guangmin Li, Ya Zhang, Shiwei Fan, Fei Yu   +3 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Exoplanet Analog Observations of Earth from Galileo Disk-integrated Photometry

The Astronomical Journal
The Galileo spacecraft had distant encounters with Earth in 1990 and 1992. Limited Solid State Imager (SSI) data acquired during these encounters has been previously presented, but the majority of the data from these Earth flybys have not been presented ...
Ryder H. Strauss, Tyler D. Robinson, David E. Trilling, Ryan Cummings, Christopher J. Smith   +4 more
doaj   +1 more source

Systemic Delivery of Divalent Europium from Ligand Screening with Implications to Direct Imaging of Hypoxia. [PDF]

J Am Chem Soc, 2022
Rashid MM, Corbin BA, Jella P, Ortiz CJ, Hassan Samee MA, Pautler RG, Allen MJ.   +6 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Direct imaging of local atomic structures in zeolite using optimum bright-field scanning transmission electron microscopy. [PDF]

Sci Adv, 2023
Ooe K, Seki T, Yoshida K, Kohno Y, Ikuhara Y, Shibata N.   +5 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Direct Imaging of Band Structure for Powdered Rhombohedral Boron Monosulfide by Microfocused ARPES. [PDF]

Nano Lett, 2023
Sugawara K, Kusaka H, Kawakami T, Yanagizawa K, Honma A, Souma S, Nakayama K, Miyakawa M, Taniguchi T, Kitamura M, Horiba K, Kumigashira H, Takahashi T, Orimo SI, Toyoda M, Saito S, Kondo T, Sato T.   +17 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Direct imaging of intracellular RNA, DNA, and liquid-liquid phase separated membraneless organelles with Raman microspectroscopy. [PDF]

Commun Biol, 2022
Samuel AZ, Sugiyama K, Ando M, Takeyama H.   +3 more
europepmc   +1 more source