Results 131 to 140 of about 2,104,910 (277)

Initial experiences with Direct Imaging of Neuronal Activity (DIANA) in humans. [PDF]

Imaging Neurosci (Camb), 2023
Hodono S, Rideaux R, van Kerkoerle T, Cloos MA.   +3 more
europepmc   +1 more source

Medipix3 Demonstration and understanding of near ideal detector performance for 60 & 80 keV electrons

, 2016
In our article we report first quantitative measurements of imaging performance for the current generation of hybrid pixel detector, Medipix3, as direct electron detector.
Ballabriga, R., Clough, R., Gough, C., Kirkland, A. I., MacInnes, R., MacLaren, I., Maneuski, D., McGrouther, D., Mir, J. A., O'Shea, V., Plackett, R., Sawada, H., Shipsey, I.   +12 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Direct Imaging of Surface Melting on a Single Sn Nanoparticle. [PDF]

Nano Lett, 2023
Kryshtal A, Bogatyrenko S, Khshanovska O.   +2 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

JWST/NIRCam Imaging of Young Stellar Objects. II. Deep Constraints on Giant Planets and a Planet Candidate Outside of the Spiral Disk Around SAO 206462

The Astronomical Journal
We present JWST/NIRCam F187N, F200W, F405N, and F410M direct imaging data of the disk surrounding SAO 206462. Previous images show a very structured disk, with a pair of spiral arms thought to be launched by one or more external perturbers.
Gabriele Cugno, Jarron Leisenring, Kevin R. Wagner, Camryn Mullin, Ruobing Dong, Thomas Greene, Doug Johnstone, Michael R. Meyer, Schuyler G. Wolff, Charles Beichman, Martha Boyer, Scott Horner, Klaus Hodapp, Doug Kelly, Don McCarthy, Thomas Roellig, George Rieke, Marcia Rieke, John Stansberry, Erick Young   +19 more
doaj   +1 more source

Direct imaging of micrometer-thick interfaces in salt-salt aqueous biphasic systems. [PDF]

Proc Natl Acad Sci U S A, 2023
Degoulange D, Pandya R, Deschamps M, Skiba DA, Gallant BM, Gigan S, de Aguiar HB, Grimaud A.   +7 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Direct Imaging of Local pH Reveals Bubble-Induced Mixing in a CO₂ Electrolyzer. [PDF]

ACS Sustain Chem Eng, 2023
Baumgartner LM, Kahn A, Hoogland M, Bleeker J, Jager WF, Vermaas DA.   +5 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source