Results 101 to 110 of about 3,701,355 (246)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
The Use of Behavioral Skills Training to Teach Components of Direct Instruction. [PDF]
Behav Anal Pract, 2021 Sherman J, Richardson J, Vedora J.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Journal of Learning Development in Higher EducationIt is reasonable to assume that a core focus of Learning Developers is student learning and the techniques we use to support this learning. It is interesting to note, therefore, that Cognitive Load Theory (CLT) – seen by some as ‘the single most ...
Steven White
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Learning Basketball Using Direct Instruction and Tactical Game Approach Methodologies. [PDF]
Children (Basel), 2021 González-Espinosa S +3 more
europepmc +1 more source
THE EFFECTIVENESS OF COLLABORATIVE WRITING METHOD TO TEACH WRITING SKILL VIEWED FROM STUDENTS’ CREATIVITY [PDF]
, 2012 This research is aimed at finding out whether: (1) Collaborative Writing is more effective than Direct Instruction to teach writing to the third semester students of State Islamic College (STAIN) of Jurai Siwo Metro in the academic year of 2012/2013 ...
Rochsantiningsih, Dewi +2 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Guidelines for Facilitating Direct Instruction of Generalized Social Behavior: Teaching the General Case. [PDF]
Behav Anal Pract, 2021 Scott TM, Dubuque EM.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source