Results 61 to 70 of about 3,701,355 (246)

The Long-Term Impact of NIFDI-Supported Implementation of Direct Instruction on Reading Achievement: An Analysis of Fifth Graders in the Baltimore City Public School System [PDF]

open access: yes, 2008
41 pagesIn the mid 1990s, in response to very low reading achievement scores, the Baltimore City Public School System (BCPSS) implemented curricular reforms. Sixteen schools used Direct Instruction.
Stockard, Jean
core   +1 more source

Developing Direct Instruction program and evaluation of its effectiveness on math problem solving skills in students with Learning Disorder [PDF]

open access: yesRavānshināsī-i Afrād-i Istis̠nāyī, 2017
Objective: The aim of this study was Developing training programs based on Direct Instruction and evaluation of its effectiveness on solving math problem in students with Learning Disorders.
masoumeh imani   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The Theoretical and Methodological Opportunities Afforded by Guided Play With Young Children

open access: yesFrontiers in Psychology, 2018
For infants and young children, learning takes place all the time and everywhere. How children learn best both in and out of school has been a long-standing topic of debate in education, cognitive development, and cognitive science. Recently, guided play
Yue Yu   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A broad look at the literature on math word problem-solving interventions for third graders

open access: yesCogent Education, 2016
Though research on effective instruction in math word problem solving is prominent at the middle and secondary levels, much less work has been done in elementary grades.
Sheri Kingsdorf, Jennifer Krawec
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Changing Mathematics and Reading Achievement with Direct Instruction: Kment Elementary School in Roseville, Michigan [PDF]

open access: yes, 2015
13 pagesThis report examines changes in mathematics and reading skills of students in a Michigan elementary school after instruction with the Direct Instruction programs Connecting Math Concepts: Comprehensive Edition (CMCCE) and Reading Mastery ...
Stockard, Jean
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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