Results 51 to 60 of about 817,469 (302)
A coupled approximate deconvolution and dynamic mixed scale model for large-eddy simulation
, 2007 Large-eddy simulations of incompressible Newtonian fluid flows with approximate deconvolution models based on the van Cittert method are reported. The Legendre spectral element method is used for the spatial discretization to solve the filtered Navier ...
Bouffanais, Roland +3 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Direct Pore‐Scale Numerical Simulation of Microbially Induced Calcium Carbonate Precipitation
Water Resources Research, 2023 Microbially induced calcium carbonate precipitation (MICP) is a promising method for eco‐friendly solutions in geotechincal engineering. MICP involves highly coupled processes in geochemistry and bacterial metabolism that take place in a porous medium ...
Mohammad Amin Razbani +2 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Direct Numerical Simulation of Laminar-Turbulent Transition on Grids with Local Refinement
Учёные записки Казанского университета: Серия Физико-математические науки, 2017 This paper considers a method of building composite grids with local refinement for direct numerical simulation of flows in a channel with transverse cylindrical rib at moderate Reynolds numbers.
D.I. Okhotnikov
doaj
, 2010 Effective modeling and numerical spectral-based propagation schemes are proposed for addressing the challenges in time-dependent quantum simulations of systems ranging from atoms, molecules, and nanostructures to emerging nanoelectronic devices.
Chen, Zuojing, Polizzi, Eric
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Direct numerical simulation of noninvasive channel healing in electrical field
Advances in Mechanical Engineering, 2017 Noninvasive channel healing is a new idea to repair the broken pipe wall, using external electric fields to drive iron particles to the destination. The repair can be done in the normal operation of the pipe flow without any shutdown of the pipeline so ...
Yi Wang, Shuyu Sun
doaj +1 more source
Numerical investigation of particles turbulent dispersion in channel flow [PDF]
, 2012 This paper investigates the performance of Reynolds-averaged Navier-Stokes model on dispersion of particles in wall turbulence. A direct numerical simulation of wall-bounded channel flow with particles suspensions was set as a benchmark.
Andersson Helge +4 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source