Results 101 to 110 of about 10,147,983 (339)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A Review on Anaerobic Digestate as a Biofertilizer: Characteristics, Production, and Environmental Impacts from a Life Cycle Assessment Perspective

Applied Sciences
Digestate valorization is essential for sustainable waste management and circular economy strategies, yet large-scale adoption faces technical, economic, and environmental challenges.
Carmen Martín-Sanz-Garrido, Marta Revuelta-Aramburu, Ana María Santos-Montes, Carlos Morales-Polo   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

WTO direct action convergence, Seattle, WA (nov. 20-28), registration application [verso]

, 1999
Alternate title: DAN registration. Affiliated web page url: www.agitprop.org/artandrevolution/wto. Also sent out as document 6 of 19 in a Direct Action Network (DAN) organizing packet; these documents are contained in a 9 X 12 inch envelope stating ...
Direct Action Network (DAN)
core  

THE CONCEPT OF RISK MANAGEMENT: AN INTEGRATED ANALYSIS BASED ON THE CRITERIA OF THE FINANCIAL CONDITION OF ENTERPRISES

Фінансово-кредитна діяльність: проблеми теорії та практики
The article is a theoretical and methodological study of risks as an important concept of enterprise management, highlighting the methodology of comprehensive risk analysis based on the criteria of the enterprise's financial condition.
Svitlana Zhukevych , Viktoria Rozheljuk , Тetiana Portovaras, Natalіa Zhuk, Pavlo Denchuk   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Resist the WTO roadshow : sponsored by the Direct Action Network Against Corporate Globalization and Global Exchange [verso]

, 1999
Alternate title: Resist the World Trade Organization roadshow. Also sent out as document 12 of 19 in a Direct Action Network (DAN) organizing packet; these documents are contained in a 9 X 12 inch envelope stating approximately 50-100 organizing packets
Direct Action Network (DAN)
core  

Corporate resilience in the ESG dimension: synergy of financial, security and marketing determinants

Journal of Business Economics and Management
This article develops an integrated model of corporate resilience in the ESG dimension, combining financial, security, and marketing determinants under conditions of growing uncertainty and systemic risks.
Ganna Likhonosova, Iryna Shevchenko, Arūnas Jaras, Roman Trishch, Andrius Stasiukynas   +4 more
doaj   +1 more source

Direct biomechanical manipulation of human gait stability: A systematic review

PLoS ONE
People fall more often when their gait stability is reduced. Gait stability can be directly manipulated by exerting forces or moments onto a person, ranging from simple walking sticks to complex wearable robotics.
Bram T. Sterke, Saher Jabeen, Patricia M. Baines, Heike Vallery, G. Ribbers, M. Heijenbrok-Kal   +5 more
semanticscholar   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source