Results 271 to 280 of about 1,378,738 (338)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Mechanobiology of the Hippo-YAP Signaling Network. [PDF]

Cold Spring Harb Perspect Biol
Tripathi BK, Irvine KD.
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Chromatin accessibility regulates age-dependent nuclear mechanotransduction. [PDF]

Proc Natl Acad Sci U S A
Liao Y, Yuan L, Sornapudi TR, Land M, Gupta R, Shivashankar GV.   +5 more
europepmc   +1 more source

Canadian Originality and the Tension between the Commonwealth and the American Standards for Copyright Protection: The Myth of Tele-Direct

, 2003
Yoav Mazeh
openalex   +1 more source

Lock-Line Entrapment in Mitral TEER: Bailout and Management. [PDF]

JACC Case Rep
Arakawa M, Kataoka A, Watanabe Y.
europepmc   +1 more source

A novel direct tension-based loading framework for accurate Mode I fracture toughness determination in brittle geomaterials

Jinwei Fu, Vahab Sarfarazi, Hadi Haeri, Soheil Abharian, Saeed Delfan   +4 more
openalex   +1 more source

Monitoring of crack growth and crack mouth opening displacement in compact tension specimens at high temperatures : Development and implementation of the Direct Current Potential Drop (DCPD) method

, 2016
Philip Malmqvist
openalex   +1 more source

The role of Lagrangian drift in the generation of surface waves by wind. [PDF]

J Fluid Mech
Seitz LR, Freilich MA, Pizzo N.
europepmc   +1 more source

The time-dependent reliability of CRTS III slab ballastless track structures based on direct probability integral method. [PDF]

Sci Rep
Wenchang Z, Xiao L, Junyan D, Huaxia Z, Qiufen T.   +4 more
europepmc   +1 more source