Illustrating the structures of bias from immortal time using directed acyclic graphs. [PDF]
Yang G, Burgess S, Schooling CM.
europepmc +1 more source
The target trial framework is a pragmatic roadmap for observational causal inference that clarifies questions, mitigates time‐related bias, and improves interpretability while acknowledging limits. With transparent protocols, appropriate methods, and suitable data, it can complement randomized trials and inform practice and policy.
Sebastian‐Edgar Baumeister +6 more
wiley +1 more source
Pentavalent rotavirus vaccine effectiveness among children in Shenzhen, China: A population-based test-negative design with directed acyclic graphs bias adjustment. [PDF]
Lin Z +11 more
europepmc +1 more source
Study Design in Clinical and Epidemiologic Research: Observational, Experimental, and Beyond
Population‐based epidemiology and clinical research are complementary and mutually reinforcing: Epidemiology quantifies disease incidence/prevalence and elucidates environmental and social determinants in populations, whereas clinical research evaluates biomarkers, therapeutics, and prognostic outcomes in patients; their convergence underpins ...
Gustavo G. Nascimento +3 more
wiley +1 more source
Learning directed acyclic graphs for ligands and receptors based on spatially resolved transcriptomic data of ovarian cancer. [PDF]
Chowdhury S +6 more
europepmc +1 more source
Directed acyclic graphs to minimise bias and optimise causal inference in SNAP-3: an observational cohort study of frailty, multimorbidity, and delirium in older surgical patients. [PDF]
Swarbrick CJ +4 more
europepmc +1 more source
Maternal Dietary Inflammatory Index and Biomarkers of Inflammation at Birth
ABSTRACT We evaluated the association between the inflammatory potential of the maternal diet during pregnancy and levels of inflammatory biomarkers measured in cord blood and maternal serum at birth. Dietary inflammatory potential was calculated using the energy‐adjusted dietary inflammatory index (E‐DII) in the French EDEN and ELFE birth cohorts ...
Courtney Dow +9 more
wiley +1 more source
Directed Acyclic Graphs in Decision-Analytic Modeling: Bridging Causal Inference and Effective Model Design in Medical Decision Making. [PDF]
Dijk SW +8 more
europepmc +1 more source
Incident Lung Cancer and Mortality: Data From Health ABC Using Periodontal Status and Tooth Loss
ABSTRACT Aim To evaluate whether periodontal parameters and tooth loss are associated with lung cancer incidence and mortality among older adults. Materials and Methods Data are from the Health, Aging and Body Composition (Health ABC) study, which included 1136 older adults who received a periodontal examination and were followed for up to 16 years ...
Taciane Menezes da Silveira +5 more
wiley +1 more source
Estimation of high-dimensional directed acyclic graphs with surrogate intervention. [PDF]
Ha MJ, Sun W.
europepmc +1 more source

