Results 91 to 100 of about 3,052,168 (293)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Synthesis of the optimum two-channel direction finder with linear scanning of the antenna pattern

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Target angular coordinates two-channel measurer synthesis and the description of operational algorithm in case of use of the antenna pattern linear scanning are described.
M. M. Bulash, S. V. Shaliapin
doaj  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Quasi-optimal discriminator of the two-channel angular coordinates measurer of the fast fluctuating signal source in the radar with linear scanning of the antenna direction pattern

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Considering the synthesis of the quasi-optimal two-channel discriminator structure of the angle meter of the fast fluctuating signal source for using a linear scanning of the antenna pattern. It is shown that the discriminator can be constructed by using
M. M. Bulash   +2 more
doaj  

DIRECTION FINDING OF HF SIGNALS SCATTERED BY IONOSPHERIC IRREGULARITIES USING SMALL SIZE ANTENNA

open access: yesRadio Physics and Radio Astronomy, 2016
Purpose: A modification of the Doppler Interferometry Technique is suggested to enable estimating angles of arrival of comparatively broadband HF signals scattered by random irregularities of the ionospheric plasma with the use of small-size near ...
V. G. Galushko   +4 more
doaj   +1 more source

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