Results 81 to 90 of about 3,070,422 (295)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Direction Finding in MIMO Radar With Unknown Mutual Coupling
Multiple-input multiple-output (MIMO) radar has received much attention due to its potentials in offering improved performance for target detection and parameter estimation.
Ce Zhang, Huiping Huang, Bin Liao
doaj +1 more source
Direction finding measurements of auroral kilometric radiation [PDF]
Direction finding measurements with plasma wave experiments onboard the Hawkeye-1 and IMP-8 satellites were used to locate the source region of auroral kilometric radiation.
Baumback, M. M. +2 more
core +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Improved PLL-based MUSIC Algorithm for Single Receiver DF Systems
In this paper we propose an improved version of a single receiver DF system that combines a PLL scheme with the MUSIC algorithm to obtain both azimuthal and zenithal angles.
Aline G. T. Duarte +2 more
doaj +1 more source
Statistical analysis of Ni nanowires breaking processes: a numerical simulation study
A statistical analysis of the breaking behavior of Ni nanowires is presented. Using molecular dynamic simulations, we have determined the time evolution of both the nanowire atomic structure and its minimum cross section (Sm(t)).
Costa-Krämer J L +9 more
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Finite Temperature Density Instability at High Landau Level Occupancy
We study here the onset of charge density wave instabilities in quantum Hall systems at finite temperature for Landau level filling $\nu>4$. Specific emphasis is placed on the role of disorder as well as an in-plane magnetic field.
A. H. MacDonald +17 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

