Results 61 to 70 of about 3,980,275 (286)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Direction Finding Using GHA Neural Networks
Al-Khawarizmi Engineering Journal, 2006 This paper adapted the neural network for the estimating of the direction of arrival (DOA). It uses an unsupervised adaptive neural network with GHA algorithm to extract the principal components that in turn, are used by Capon method to estimate the DOA,
N. H. Abbas
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Direction Finding of ELF Emissions in Auroral Zone
Antarctic Record, 1976 The observation of arrival direction for elliptically polarized ELF and VLF electromagnetic waves, based on a new method developed by TSURUDA and HAYASHI (1975), was carried out at Syowa Station in Antarctica from March, 1974 to January, 1975.
Natsuo SATO, Kanji HAYASHI
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Improved VHF direction finding system [PDF]
, 1969 Direction finding device operating at very high frequencies requires a loop antenna, mechanical rotation, and large structures. The system is applicable to an unmanned configuration.
Neff, H., Graf, E. R.
core
TDOA-Based Acoustic Direction Finding
, 2018 This chapter focuses on estimating the azimuth and elevation angles of a sound emitter based on time-difference-of-arrival (TDOA) measurements using an array of acoustic sensors.
Kegen Yu, Xunxue Cui, Songsheng Lu
core +1 more source
PERFORMANCE ANALYSIS FOR DIRECTION-FINDING CIRCULAR ANTENNA ARRAY
Известия высших учебных заведений России: Радиоэлектроника, 2018 This paper considers circular antenna arrays comprised of symmetrical dipole radiators applied in communication, navigation and monitoring systems. Despite their widespread use, a number of significant issues is underinvestigated.
Svyatoslav V. Ballandovich +3 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source