Results 51 to 60 of about 669,386 (303)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

PASSIVE DIRECTION FINDING USING AMPLITUDE AND PHASE COMPARISON TECHNIQUES

open access: yes, 2014
Amplitude and phase comparison methods are practical direction finding (DF) techniques for electronic support and electronic intelligence systems. The combination of amplitude and phase comparison methods improves the direction finding accuracy and at ...
Serin, Mahmut   +3 more
core   +2 more sources

Direction Finding Using GHA Neural Networks

open access: yesAl-Khawarizmi Engineering Journal, 2017
This paper adapted the neural network for the estimating of the direction of arrival (DOA). It uses an unsupervised adaptive neural network with GHA algorithm to extract the principal components that in turn, are used by Capon method to estimate the DOA,
N. H. Abbas
doaj  

Direction‐of‐arrival estimation via coarray‐domain RELAX algorithm with source number estimation

open access: yesIET Radar, Sonar & Navigation
A modified RELAX algorithm based on iterative coarray‐domain beamforming for fast source direction‐of‐arrival (DOA) estimation with fully augmentable sparse arrays is proposed.
Fauzia Ahmad, Moeness G. Amin
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Direction finding with a circularly rotated antenna

open access: yes, 2000
In this work, a new algorithm for multiple emitter direction finding by using a single antenna moving along a circular trajectory is proposed. The problem is formulated by taking the Doppler frequency shift, caused by the movement of the antenna.
Sen, E, Koc, AT, Tanik, Y
core   +1 more source

A spectrum efficient cellular base-station antenna architecture [PDF]

open access: yes, 1992
A concept is considered according to which using the spatial distribution of the users acquired by an array on reception, an antenna system can dynamically assign single narrow beams to illuminate lone mobiles, and broad beams to the numerous groupings ...
Swales, SC   +5 more
core   +1 more source

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