Results 71 to 80 of about 13,242,853 (317)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Direction Finding Using GHA Neural Networks

open access: yesAl-Khawarizmi Engineering Journal, 2017
This paper adapted the neural network for the estimating of the direction of arrival (DOA). It uses an unsupervised adaptive neural network with GHA algorithm to extract the principal components that in turn, are used by Capon method to estimate the DOA,
N. H. Abbas
doaj  

Assisting Maritime Search and Rescue (SAR) Personnel with AI-Based Speech Recognition and Smart Direction Finding

open access: yesJournal of Marine Science and Engineering, 2020
Communication for processing relevant information plays a paramount role in developing a comprehensive understanding of Search and Rescue (SAR) situations and conducting operations in a successful and reliable manner.
Aylin Gözalan   +6 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Direction Finding Using GHA Neural Networks

open access: yesAl-Khawarizmi Engineering Journal, 2006
This paper adapted the neural network for the estimating of the direction of arrival (DOA). It uses an unsupervised adaptive neural network with GHA algorithm to extract the principal components that in turn, are used by Capon method to estimate the DOA,
N. H. Abbas
doaj  

Direction‐of‐arrival estimation via coarray‐domain RELAX algorithm with source number estimation

open access: yesIET Radar, Sonar & Navigation
A modified RELAX algorithm based on iterative coarray‐domain beamforming for fast source direction‐of‐arrival (DOA) estimation with fully augmentable sparse arrays is proposed.
Fauzia Ahmad, Moeness G. Amin
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Direction Finding of ELF Emissions in Auroral Zone

open access: yesAntarctic Record, 1976
The observation of arrival direction for elliptically polarized ELF and VLF electromagnetic waves, based on a new method developed by TSURUDA and HAYASHI (1975), was carried out at Syowa Station in Antarctica from March, 1974 to January, 1975.
Natsuo SATO, Kanji HAYASHI
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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