Results 51 to 60 of about 22,098 (307)

Directional del-derivative and Curves on n-dimensional Time Scales

, 2009
Sarikaya, Mehmet/0000-0003-3856-6360; YILDIRIM, Huseyin/0000-0001-8855-9260The general ideal in this paper is to study a differential calculus for multivariable functions, directional del-derivative and curves of parametric equations on n-dimensional ...
İlarslan, Kazim, Sarıkaya, Mehmet Zeki, Yildirim, Hueseyin, Yıldırım, Hüseyin, Sarikaya, Mehmet Zeki, Aktan, Nesip   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Maximum Aligned Directional Derivative (MADD) Technique for Planar Structure Analysis in Space

The Astrophysical Journal Supplement Series, 2023
Interplanetary discontinuities are the most common intermittent structures in the solar winds, whose jump conditions conform to the Rankine–Hugoniot relations. The identification and analysis of such planar structures rely on an accurate determination of
Y. Y. Liu, H. S. Fu, J. B. Cao, C. X. Du, W. Z. Zhang   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The lai inversion based on directional second derivative using hyperspectral data

, 2008
Leaf area index (LAI) is an important structure parameter of vegetation system. The quantitative remote sensing can offer two dimensional distribution of LAI.
Liu Xiao-chen, Qing-jiu, Tian, Xi-ru, Xu, Xu Xi-ru, Wen-jie, Fan, Fan Wen-jie, Tian Qing-jiu, Xiao-chen, Liu   +7 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The Avriel-Ben-Tal algebraic operations approach for a short version proof of the Karush-Kuhn-Tucker optimality conditions

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2017
In this paper, by using (h, ϕ)-generalized directional derivative and (h, ϕ)-generalized gradient, the authors directly derives the Karush- Kuhn-Tucker conditions by applying a corollary of Farkas lemma under the Mangasarian-Fromovitz constraint ...
Cornaciu Veronica, Ioana Ileana
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Some Results on Composition of Analytic Functions in a Unit Polydisc

Universal Journal of Mathematics and Applications
The manuscript is an attempt to consider all methods which are applicable to investigation a directional index for composition of an analytic function in some domain and an entire function.
Petro Kurliak, Oleh Skaskiv, Andriy Bandura   +2 more
doaj   +1 more source

Approximation of Directional Step Derivative of Complex-Valued Functions Using a Generalized Quaternion System

Axioms, 2021
The step derivative of a complex function can be defined with various methods. The step direction defines a basis that is distinct from that of a complex number; the derivative can then be treated by using Taylor series expansion in this direction.
Ji-Eun Kim
doaj   +1 more source