Results 81 to 90 of about 648 (164)

Herpes zoster admissions: The majority of patients are not immunised

JEADV Clinical Practice, Volume 4, Issue 1, Page 314-315, March 2025.
Mina Raahimi, Martin Hartmann
wiley   +1 more source

Identifying the White Matter Pathways Involved in Multiple Sclerosis-Related Tremor Using Diffusion Tensor Imaging [PDF]

, 2023
Background Tremor affects up to 45% of patients with Multiple Sclerosis (PwMS). Current understanding is based on insights from other neurological disorders, thus, not fully addressing the distinctive aspects of MS pathology. Objective To characterize
Bayoumi, Ahmed, Gabr, Refaat E, Hasan, Khader M, Kamali, Arash, Keser, Zafer, Lincoln, John A, Patino, Jorge, Pedroza, Claudia, Schiess, Mya C, Thomas, Joseph A, Wolinsky, Jerry S   +10 more
core   +1 more source

Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing–remitting multiple sclerosis, the ProVal-MS study

Neurological Research and Practice
Introduction In Multiple Sclerosis (MS), patients´ characteristics and (bio)markers that reliably predict the individual disease prognosis at disease onset are lacking.
Antonios Bayas, Ulrich Mansmann, Begum Irmak Ön, Verena S. Hoffmann, Achim Berthele, Mark Mühlau, Markus C. Kowarik, Markus Krumbholz, Makbule Senel, Verena Steuerwald, Markus Naumann, Julia Hartberger, Martin Kerschensteiner, Eva Oswald, Christoph Ruschil, Ulf Ziemann, Hayrettin Tumani, Ioannis Vardakas, Fady Albashiti, Frank Kramer, Iñaki Soto-Rey, Helmut Spengler, Gerhard Mayer, Hans Armin Kestler, Oliver Kohlbacher, Marlien Hagedorn, Martin Boeker, Klaus Kuhn, Stefan Buchka, Florian Kohlmayer, Jan S. Kirschke, Lars Behrens, Hanna Zimmermann, Benjamin Bender, Nico Sollmann, Joachim Havla, Bernhard Hemmer, the ProVal-MS study group   +37 more
doaj   +1 more source

Psoriasiform dermatitis following ocrelizumab in relapsing-remitting multiple sclerosis: Case report and literature review [PDF]

We present a case of a 30-year-old man with relapsing-remitting multiple sclerosis who developed psoriasiform dermatitis following his second course of ocrelizumab. This resolved with topical therapies and discontinuation of treatment.
Alison, Hassett, Emma, Callanan, Floriana, De Angelis, Huseyin, Huseyin, Kay, Polly, Mara, Sittampalam, Sara, Collorone, Vesela, Petkova   +7 more
core  

Early prognostic factors of multiple sclerosis [PDF]

, 2022
Background: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS). Although great advances in MS treatment have been made, it remains one of the most common causes of neurological disability in young adults globally.
Kuutti, Katariina
core  

METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD DIROXIMEL FUMARATE IN BULK DRUG AND IT'S DOSAGE FORM

, 2023
A Diroximel Fumarate is clinically used in combination in the treatment of anti-inflammatory agent. The present work deals with the RP-HPLC methods for Diroximel Fumarate in pharmaceutical formulation. attempts were made to develop rp-hplc method for estimation of diroximel fumarate bulk drug and formulation For the rp hplc method, agilent (s.k ...
openaire   +1 more source

Pharmacological Modulation of the Nrf2–Keap1 Pathway in Diabetes: Mechanisms, Therapeutic Advances, and Future Directions [PDF]

Diabetes mellitus remains a major global challenge driven by oxidative stress, inflammation, and metabolic imbalance. The nuclear factor erythroid 2–related factor 2 (Nrf2)–Kelch-like ECH-associated protein 1 (Keap1) pathway acts as a pivotal ...
Bharti, Pooja, Chaudhary, Rama, Jain, Ashita, Kumar, Abhishek, Kumar, Ankit, Kumar, Sanjeev, Mishra, Shivdeep, Saxena, Amar, Saxena, Shrestha, Saxena, Yash, Singh, Chandrabhan   +10 more
core   +2 more sources

Smouldering Inflammation in Multiple Sclerosis – A PET Imaging Study on Prediction of Disease Progression and Effects of Treatment [PDF]

Background: Multiple sclerosis (MS) is the most common inflammatory and neurodegenerative autoimmune disease of the central nervous system in young adults, where the inflammatory reaction causes destruction of the myelin sheet surrounding the neurons in ...
Sucksdorff, Marcus
core  

Recommendations for essential medicines for multiple sclerosis in low-resource settings [PDF]

Background: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that, when untreated, can lead to significant disability in young adults.
Abkari N. E., Avasarala J., Baldin E., Banerjee T. K., Bogdanovic I., Bove R., Chawla D. K., Costello K., Del Giovane C., Filippini G., Foschi M., Gonzalez-Lorenzo M., Helme A., Jacobs D., Kalincik T., Laurson-Doube J., Mantel-Teeuwisse A., McDonell J., Minozzi S., Navas C., Nonino F., Ojo O. O., Ozcan B., Pasi E., Peryer G., Piggott T., Prato Chichiraldi A., Ridley B., Rijke N., Saylor D., Schunemann H., Sokhi D. S., Traboulsee A., Tramacere I., Tye J. S. N., Vecchi S., Viswanathan S., Xie F., Zeineddine M.   +38 more
core   +1 more source

Assessing neuroprotective effects of diroximel fumarate and siponimod via modulation of pacemaker channels in an experimental model of remyelination

Experimental Neurology
Cuprizone (CPZ)-induced alterations in axonal myelination are associated with a period of neuronal hyperexcitability and increased activity of hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels in the thalamocortical (TC) system.
Laura, Vinnenberg, Nicole, Rychlik, Tengiz, Oniani, Brandon, Williams, John A, White, Stjepana, Kovac, Sven G, Meuth, Thomas, Budde, Petra, Hundehege   +8 more
openaire   +2 more sources