Results 11 to 20 of about 2,978,128 (338)
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Customized Solutions for Today\u27s Workforce: The Job Accommodation Network [PDF]
[Excerpt] The Job Accommodation Network (JAN) is a free and confidential consulting service for employers that expands employment opportunities for individuals with disabilities by providing: ■ Individualized worksite accommodation solutions ■ Technical ...
Office of Disability Employment Policy
core +1 more source
CD9‐association with PIP2 areas is regulated by a CD9 salt bridge
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi+2 more
wiley +1 more source
Employers and the ADA: Myths and Facts [PDF]
[Excerpt] The Americans with Disabilities Act (ADA) is a landmark federal law that protects the rights of people with disabilities by eliminating barriers to their participation in many aspects of living and working in America.
Office of Disability Employment Policy
core +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel+8 more
wiley +1 more source
Investing In People: Job Accommodation Situations and Solutions [PDF]
[Excerpt] When thinking about accommodations, the focus should not be on the person’s disability but rather on essential job tasks and the physical functions necessary to complete them.
Office of Disability Employment Policy
core +1 more source
Spinal Cord Abnormalities in Early Pediatric Multiple Sclerosis
ABSTRACT Spinal cord lesions and atrophy in the cervical region are common in adult multiple sclerosis (MS) and correlate with disability. Whether similar abnormalities occur in pediatric MS patients is largely unknown. Clinical and MRI evaluations were performed in 38 pediatric MS patients and 13 healthy controls (HC).
Monica Margoni+7 more
wiley +1 more source
Strategic Connections: Recruiting Candidates with Disabilities [PDF]
[Excerpt] Many individuals with disabilities possess precisely these attributes. Yet, as a whole, individuals with disabilities represent one of the largest untapped pools of skills and talent in the U.S. According to the U.S. Census Bureau, just over 60
Office of Disability Employment Policy
core +1 more source
Care work: dreaming disability justice
Care Work: Dreaming Disability Justice is a collection of visionary essays on vibrant organizing for Disability Justice that is gathering momentum across the unceded and occupied Indigenous territo...
A. de Bie+3 more
semanticscholar +1 more source
Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability
ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion+15 more
wiley +1 more source