Results 121 to 130 of about 974,850 (342)

Ergonomic Standards for Disabled People in Pedestrian Areas : Results from Leeds Observation Work 1988/89 [PDF]

, 1989
This working paper is one of a series (WP 252, 253, 254, 255, 274, 275), describing work undertaken under contract to TRRL investigating design guidance for pedestrian areas and footways to satisfy the needs of disabled and elderly people.
Berrett, B., Leake, G.R., May, A.D., Parry, T.   +3 more
core   +1 more source

DV3-IBi_YOLOv5s: A Lightweight Backbone Network and Multiscale Neck Network Vehicle Detection Algorithm

Sensors
Vehicle detection is a research direction in the field of target detection and is widely used in intelligent transportation, automatic driving, urban planning, and other fields.
Liu Wang, Lijuan Shi, Jian Zhao, Chen Yang, Haixia Li, Yaodong Jia, Haiyan Wang   +6 more
doaj   +1 more source

A comparative examination of policy and models of disability in Korea and the UK [PDF]

, 2012
Over the last three decades, the understanding of disability has changed substantially, changes in theoretical debates and policy on disability now encourage society to understand and treat disabled people as ordinary citizens.
Brandon, Toby, Hwang, Se Kwang
core  

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Barriers to accessibility and availability of safe abortion services among young women in Nepal: a mixed-methods study

BMC Public Health
Background Despite Nepal’s progressive legal framework permitting abortion, young women continue to face barriers in accessing safe abortion services (SAS), leading to preventable maternal mortality and morbidity.
Radhika Ghimire, Shreesti Sharma, Aliza Singh, Rajan Bhusal, Laxmi Tamang   +4 more
doaj   +1 more source

Technologies for the Disabled [PDF]

, 2017
Nowadays computers have taken the dominant role in our society.Most jobs now require access to computers and the Internet. But what happens if a person is blind, deaf or physically disabled?
Grechikhina, Julia, Martynenko, A.A., Nechai, N.M.   +2 more
core  

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Complete Correction following Temporary Hemiepiphysiodesis using 2-hole Reconstruction Plates among Skeletally Immature Patients with Angular Deformities around Knees: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association
Introduction: Studies have shown that 2-hole reconstruction plates can be used effectively as tension band plates for temporary hemiepiphysiodesis.
Tarun Kumar Rajbhandary, Subhash Regmi, Yam Prakash Gurung, Bibek Banskota, Satish Prasad Barnawal, Ashok Kumar Banskota   +5 more
doaj   +1 more source

Disability Studies: What’s the Point? [PDF]

, 2003
[Excerpt] While the content of these courses had much to offer in terms of furthering our understanding of the experience of ‘chronic illness’ and the ensuing economic and social outcomes in terms of daily living for disabled people and their families ...
Barnes, Colin
core   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source