Results 121 to 130 of about 87,813 (301)

Synthesis of S-Glycoside Building Blocks as Mimetics of the Repeating d-GlcN-α-1,4-d-GlcA Heparan Sulfate Disaccharide

Molecules
Heparan sulfate (HS), a sulfated linear carbohydrate that decorates the cell surface and extracellular matrix, is a key regulator of biological processes.
Conor O’Shea, Gavin J. Miller
doaj   +1 more source

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation.

, 2010
OBJECTIVE: Elevated serum levels of the acute-phase protein serum amyloid A (SAA) are a marker for active rheumatoid arthritis (RA), and SAA can also be found in the tissues of patients with active RA.
Björkman, Lena, Bylund, Johan, Dahlgren, Claes, Karlsson, Anna, Raynes, John G, Shah, Chandrabala   +5 more
core   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song, HyunJi Lee, Youngshik Choe, Hyeyoung Lee   +3 more
wiley   +1 more source

Controlling the Assembly of Ureido‐Pyrimidinone Supramolecular Monomers by Tuning the Hydrophilic‐Hydrophobic Balance

Journal of Polymer Science, EarlyView.
In this study, the self‐assembly behavior of water‐compatible UPy‐based supramolecular monomers with varying hydrophilic‐hydrophobic balances is systematically investigated. Experimental and computational analyses reveal that the molecular monomer design is pivotal in steering the self‐assembly properties, highlighting the role of alkyl‐urea spacers in
Riccardo Bellan, Annalisa Cardellini, Claudio Perego, Lars J. M. M. Paffen, Laura Rijns, Giovanni M. Pavan, Patricia Y. W. Dankers   +6 more
wiley   +1 more source

Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450_(BM3) demethylases [PDF]

, 2009
Polysaccharides comprise an extremely important class of biopolymers that play critical roles in a wide range of biological processes, but the synthesis of these compounds is challenging because of their complex structures.
Arnold, Frances H., Bastian, Sabine, Bennett, Clay S., Chen, Mike M., Fu, Yu, Greenberg, William A., Lewis, Jared C., Mitsuda, Yuuichi, Wong, Chi-Huey   +8 more
core   +1 more source

In Silico Structural Analysis of Human β‐Glucuronidase for Antibody–Drug Conjugates Optimization

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Human β‐glucuronidase (HGUSB), a key lysosomal glycosyl hydrolase for the degradation pathway of glycosaminoglycans (GAGs), plays a crucial role in cell proliferation and inflammation, making it a promising target for novel therapeutic strategies including antibody‐drug conjugates (ADCs) with β‐glucuronic linkers.
Giorgia Canini, Simona Saporiti, Crescenzo Coppa, Mara Rossi, Fabio Centola, Alessandro Arcovito   +5 more
wiley   +1 more source

A scheme for the identification of the carbohydrates [PDF]

, 1921
Thesis (M.A.)--Boston ...
Stevens, Helen Mary
core   +1 more source

Deciphering Branched Galactomannan Structures via Multistage Ion Mobility MS and MSn Fragmentation (Multistage IMSn)

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Hemicelluloses are abundant carbohydrate components in plant cell walls. They play a crucial structural role in binding cellulose microfibrils, in addition to other biological functions. Their high structural variability directly influences their biological properties, making it important to establish a structure–function ...
Rania Benazza, Mathieu Fanuel, Hélène Rogniaux, David Ropartz   +3 more
wiley   +1 more source

Molecular Structure of Endotoxins from Gram-negative Marine Bacteria: An Update (review) [PDF]

, 2007
A. Molinaro, E. L. Nazarenko, LANZETTA, ROSA, LEONE, SERENA, M. Parrilli, SILIPO, ALBA   +5 more
core   +1 more source

alpha -Lactalbumin (LA) Stimulates Milk beta-1,4-Galactosyltransferase I (beta 4Gal-T1) to Transfer Glucose from UDP-glucose to N-Acetylglucosamine: CRYSTAL STRUCTURE OF beta 4Gal-T1·LA COMPLEX WITH UDP-Glc* [PDF]

, 2001
beta-1,4-Galactosyltransferase 1 (Gal-T1) transfers galactose (Gal) from UDP-Gal to N-acetylglucosamine (GlcNAc), which constitutes its normal galactosyltransferase (Gal-T) activity.
Qasba, Pradman K., Ramakrishnan, Boopathy, Shah, Premal S.   +2 more
core