Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development
Small, EarlyView.Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen +7 more
wiley +1 more source
Structural and Thermodynamic Analyses of Solute-binding Protein from Bifidobacterium longum Specific for Core 1 Disaccharide and Lacto-N-biose I [PDF]
, 2008 Ryuichiro Suzuki +11 more
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Small, EarlyView.Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
High Performance Liquid Chromatography-Based Reevaluation of Disaccharides Produced upon Incubation of Sugarcane Vacuoles with UDP-Glucose [PDF]
, 1988 Andrew Maretzki, Margaret Thom
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Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Primary metabolites in root exudates are essential for plant nutrition and rhizosphere microbiome function, potentially responding sensitively to climate warming. However, the effects of long‐term soil warming on exudate metabolites in forests remain unclear.
Xiaofei Liu +6 more
wiley +1 more source
Immune Responses Following Administration of Whole Gamma Irradiated SARS-CoV-2 Vaccine Stabilized With Disaccharide Trehalose on Syrian Hamster Model [PDF]
, 2023 Farahnaz Motamedi-Sedeh +5 more
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Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
The FEBS Journal, EarlyView.CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson +10 more
wiley +1 more source
THE STUDY OF THE RHEOLOGICAL PROPERTIES OF PECTIN GELS WITH MONO - AND DISACCHARIDES
, 2016 Antonella Dorohovich +2 more
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Identification and Characterization of aβ1,3-Glucosyltransferase That Synthesizes the Glc-β1,3-Fuc Disaccharide on Thrombospondin Type 1 Repeats [PDF]
, 2006 Krisztina Kozma +7 more
openalex +1 more source