Results 31 to 40 of about 52,667 (115)

Buxusoside, a Flavonoid Disaccharide from

Natural Product Communications, 2017
A new flavonoid diglycoside named buxusoside ( 1 ), together with its aglycone chrysosplenol-D ( 2 ), as well as 4’, 5-dihydroxy-3,6,7-trimethoxyflavone ( 3 ) and 3’,4’,5-trihydroxy-3,6,7-trimethoxyflavone ( 4 ), were isolated from the 70% EtOH extract ...
Min Wang, Guo-Bo Xu, Jun Liu, Yue-Hao Zhang, Jun-Hong Liu, Jing Li, Meng Zhou, Yao-Hua Xiao, Xun He, Shang-Gao Liao   +9 more
doaj   +1 more source

Methyl 3-O-α-d-mannopyranosyl β-d-glucopyranoside tetrahydrate

Acta Crystallographica Section E, 2008
The title compound, C13H24O11·4H2O, forms extended hydrogen-bonded networks. These are present between disaccharides, but not as inter-residue hydrogen bonds, as well as to water molecules that in addition form an intermolecular chain of hydrogen ...
Lars Eriksson, Göran Widmalm
doaj   +1 more source

Evaluation of Two Methods for Quantification of Glycosaminoglycan Biomarkers in Newborn Dried Blood Spots from Patients with Severe and Attenuated Mucopolysaccharidosis Type II

International Journal of Neonatal Screening, 2022
All newborn screening (NBS) for mucopolysaccharidosis-I and -II (MPS-I and MPS-II) is carried out via the measurement of α-iduronidase (IDUA) and iduronate-2-sulfatase (IDS) enzymatic activity, respectively, in dried blood spots (DBS).
Zackary M. Herbst, Leslie Urdaneta, Terri Klein, Barbara K. Burton, Khaja Basheeruddin, Hsuan-Chieh Liao, Maria Fuller, Michael H. Gelb   +7 more
doaj   +1 more source

Synthesis of Disaccharides Containing 6-Deoxy-a-L-talose as Potential Heparan Sulfate Mimetics

Molecules, 2012
A 6-deoxy-a-L-talopyranoside acceptor was readily prepared from methyl a-L-rhamnopyranoside and glycosylated with thiogalactoside donors using NIS/TfOH as the promoter to give good yields of the desired a-linked disaccharide (69–90%).
Vito Ferro, Tomislav Karoli, Jon K. Fairweather, Ligong Liu   +3 more
doaj   +1 more source

Precision-Engineered Dermatan Sulfate-Mimetic Glycopolymers for Multi-Targeted SARS-CoV-2 Inhibition

Marine Drugs
The ongoing COVID-19 pandemic, caused by SARS-CoV-2, continues to pose major global health challenges despite extensive vaccination efforts. Variant escape, waning immunity, and reduced vaccine efficacy in immunocompromised populations underscore the ...
Lihao Wang, Lei Gao, Chendong Yang, Mengfei Yin, Jiqin Sun, Luyao Yang, Chanjuan Liu, Simon F. R. Hinkley, Guangli Yu, Chao Cai   +9 more
doaj   +1 more source

Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance

Communications Biology, 2022
The disaccharide trehalose is a synergistic cosolute and key biomarker of desiccation tolerance in tardigrades.
Kenny Nguyen, Shraddha KC, Tyler Gonzalez, Hugo Tapia, Thomas C. Boothby   +4 more
doaj   +1 more source

Isolation of Keratan Sulfate Disaccharide-branched Chondroitin Sulfate E from Mactra chinensis

Bio-Protocol, 2017
Glycosaminoglycans (GAGs) including chondroitin sulfate (CS), dermatan sulfate (DS), heparin (HP), heparan sulfate (HS) and keratan sulfate (KS) are linear, sulfated repeating disaccharide sequences containing hexosamine and uronic acid (or galactose in ...
Kyohei Higashi, Toshihiko Toida
doaj   +1 more source

Natural pentafuranosylnucleos(t)ides and their analogs: structure, functions, synthesis, and perspective of medical application [PDF]

Exploration of Drug Science
Pentafuranosylnucleos(t)ides represent a class of natural compounds regulating diverse cell functions being preferably components of biopolymers and also participating as cyclic regulatory low-molecular ligands.
Dmitrii Platov, Anna Kozlova, Cyril Alexeev, Mikhail Drenichev   +3 more
doaj   +1 more source

Convergent synthesis of the tetrasaccharide repeating unit of the cell wall lipopolysaccharide of Escherichia coli O40

Beilstein Journal of Organic Chemistry, 2012
A tetrasaccharide repeating unit corresponding to the cell-wall lipopolysaccharide of E. coli O40 was synthesized by using a convergent block glycosylation strategy.
Abhijit Sau, Anup Kumar Misra
doaj   +1 more source

Streptococcal phosphotransferase system imports unsaturated hyaluronan disaccharide derived from host extracellular matrices.

PLoS ONE, 2019
Certain bacterial species target the polysaccharide glycosaminoglycans (GAGs) of animal extracellular matrices for colonization and/or infection. GAGs such as hyaluronan and chondroitin sulfate consist of repeating disaccharide units of uronate and amino
Sayoko Oiki, Yusuke Nakamichi, Yukie Maruyama, Bunzo Mikami, Kousaku Murata, Wataru Hashimoto   +5 more
doaj   +1 more source