Results 51 to 60 of about 2,237 (266)

Status and Prospect of Thermal Analysis of Train Brake Discs

机车电传动, 2019
Disc brake is widely used for railway vehicles and cars. During the braking process, the brake disc and the brake shoe generate a large amount of heat, which affects the braking performance, so it is necessary to perform thermal analysis on the brake ...
Yuecheng NIU, Fu LI, Xinrong LI, Jincheng LI   +3 more
doaj  

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

A Reconfigurable Memristive Spiking Neuron Enabling Advanced Neuromorphic Computing

Advanced Science, EarlyView.
Pek Jun Tiw and co‐workers develop a reconfigurable memristive neuron that can exhibit four spiking behaviors with freely tunable spike train parameters. The neuron supports multiplexed spike encoding of multiple pieces of information. It also supports advanced neural network strategies, such as neural heterogeneity and dynamic mode switching ...
Pek Jun Tiw, Yuqi Li, Zhongyuan Li, Qihang Ding, Yuzhe Wang, Jiarong Wang, Yuchao Yang   +6 more
wiley   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Effect of Temperature Variations on Brake Squeal Characteristics in Disc Brake Systems

Engineering Proceedings
Brake squeal is an undesirable high-frequency noise caused by vibrations induced by friction in disc brake systems. The noise is strongly affected by temperature, as this influences the material properties of the friction pair and the dynamic behaviour ...
Akif Yavuz, Osman Taha Sen, Mustafa Enes Kırmacı, Tolga Gündoğdu   +3 more
doaj   +1 more source

Full-Scale Simulation and Experimental Study of Heat Transfer in Landing Gear Brake Discs for Medium-Sized Passenger Aircraft

Applied Sciences
Aircraft brake discs undergo rapid temperature rises during braking, critically impacting safety, lifespan, and adjacent components. Therefore, it is particularly important to study the heat transfer mechanism during the braking process and predict the ...
Qingtang Meng, Hangming Shen, Bingchu Li, Zongxia Jiao   +3 more
doaj   +1 more source

Defining the Temperature Change of the Brake Disc

Acta Technica Jaurinensis, 2018
In the article the thermal analysis of the brake disc and separator disc of a high performance power machine will be presented. As example an agricultural vehicle with weight of 30000 kg and maximum travel speed of 40 km/h will be taken.
Melinda Menyhártné Baracskai
doaj   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

MODAL AND THERMAL-MECHANICAL COUPLING ANALYSIS INAUTOMOTIVE DISC BRAKE MECHANISM

Jixie qiangdu, 2017
Brake pad is vibrating when it is friction contact with the brake disc surface in automotive disc brake mechanism.When the vibration rate is close to its natural frequency of the material.
BI HouHuang, HE JiaNing, LI ShiJin, GUO Kai   +3 more
doaj  

Shape Optimization Design of Brake System Based on Opti Struct

Journal of Harbin University of Science and Technology, 2018
Due to friction heat effect or severe vibration and other factors，the performance of automobile brake is insufficient，according to natural frequency theory of the principle of dynamics，Firstly，the simulation software of OptiStruct is used to analyze the ...
CHEN Zai-fa
doaj   +1 more source