Results 61 to 70 of about 36,485 (306)

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

PERANCANGAN ALAT PERAGA SISTEM REM CAKRAM DAN TROMOL MOBIL SUZUKI CARRY 1000 [PDF]

, 2008
In the vehicles, there are many components which has important role beside the major role as a transportation tool. And each of vehicles has one of the parts which important like brake. It is used to stop the vehicle when it runs or parks.
Aminullah, Akhmad
core  

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

ANALISIS KEAUSAN KAMPAS REM PADA DISC BRAKE DENGAN VARIASI LUBANG DISC BRAKE

JURNAL ILMIAH MOMENTUM, 2019
Disc brake merupakan salah satu komponen kendaraan bermotor yang berfungsi untuk memperlambat atau menghentikan laju kendaraan khususnya kendaraan darat yaitu sebuah besi yang berbentuk piringan yang dijepit oleh kampas rem menggunakan caliper yang digerakkan oleh piston.
Dody Samwijaya, Darmanto Darmanto, Imam Syafa’at   +2 more
openaire   +2 more sources

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Status and Prospect of Thermal Analysis of Train Brake Discs

机车电传动, 2019
Disc brake is widely used for railway vehicles and cars. During the braking process, the brake disc and the brake shoe generate a large amount of heat, which affects the braking performance, so it is necessary to perform thermal analysis on the brake ...
Yuecheng NIU, Fu LI, Xinrong LI, Jincheng LI   +3 more
doaj  

Effects of material properties on generation of brake squeal noise using finite element method

Latin American Journal of Solids and Structures
This research paper is concerned with the disc brake squeal problem for passenger cars. The aim of the present research is developing a finite element model of the disc brake assembly in order to improve understanding of the influence of Young's modulus ...
Ali Belhocine, Nouby Mahdi Ghazaly
doaj   +1 more source

Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems

Advanced Science, EarlyView.
A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller, Amelie Maribel Schneider, Ellen Sjule, Renhua Sun, Xiao Han, Luca Andronico, Edward Jenkins, Michael Dustin, Adnane Achour, Erdinc Sezgin   +9 more
wiley   +1 more source

Electroactive Metal–Organic Frameworks Enabling Unidirectional Electrochemical Capacitors and Logic Gates (MOF‐CAPode)

Angewandte Chemie, EarlyView.
MOF‐CAPodes are introduced by pairing various p‐MOFs with an n‐MOF as electrode materials in a battery‐like assembly. The devices achieve high figures of merit (RRI = 23.5; RRII = 94.4%) and perform excellently in prototypical logic gates (AND, OR) highlighting a new direction for ionological systems based on electroactive MOFs.
Tim Engelhardt, Leonid Shupletsov, Christin Gellrich, Cécilia Bauden, Przemyslaw Galek, Ahmed Bahrawy, Sonila Xhafa, Irena Senkovska, Julia Grothe, Stefan Kaskel   +9 more
wiley   +2 more sources

Nanoscale Covalent Organic Framework Confinement Enables Ultratough and Hyperelastic Hydrogels Applied as High‐Performance Electrolytes

Advanced Science, EarlyView.
Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan, Wei Zhao, Hao Wang, Lu Wu, Yedong Ma, Binting Huang, Hantao Xu, Xueyan Liu, Siqi Liu, Xinyu Dong, Xiaoyang Zhang, Wei Zhai, Weiwei Zhang, Lin Xu, Dan Zhao, Chaobin He   +15 more
wiley   +1 more source